https://www.selleckchem.com/products/vorapaxar.html The direct determination Mn2+ using carboxymethyl chitosan crosslinked with cyclodextrin containing hydrogen-bonded NC QDs (NC QD/CCSCD nanocomposites). The probable mechanism of the NC QD/CCSCD nanocomposites' fluorescence was quenched by Mn2+ could be interpreted as acyclic crown ether chelation. Mn2+ induced the NC QD/CCSCD clusters assembly to form large aggregates, which resulted in aggregation-caused quenching. The linear detection (I = 479.93-15.94C (R2 = 0.9954)) can be established at Mn2+ concentrations from 0 to 21.11 × 10-6 mol/L. Common metal ions, except iron and magnesium, showed minimal effect on detection. It could satisfy the standard range of Mn2+ in actual water samples. The method which using chelating assembly mechanism to build a novel sensor would provide a new model for the application of polymer materials in this field, but the precise assembly of polymer is an unsolved challenge.Thermosensitive chitosan hydrogels have been widely used in drug delivery and tissue repair, but further applications of these hydrogels have been limited by their weak mechanical strength and poor bioactivity. A thermoresponsive hydrogel formed by conjugating recombinant human collagen-peptide (RHC) with chitosan might be better suited for cell encapsulation and wound repair. RHC-chitosan hydrogels were prepared and tested, and the results showed that moderate RHC conjugation led to hydrogels with lower gelation temperature. The prepared RHC-containing hydrogels showed superior mechanical strength to chitosan-only hydrogels. Additionally, cells exhibited superior viability when cultured with RHC-modified hydrogels compared with hydrogels that had not been conjugated with RHC. Finally, RHC-chitosan hydrogels were injected onto the backs of rats with second-degree burns and promoted cell infiltration, vessel formation, and wound healing. Overall, the use of RHC-chitosan hydrogels is a promising and effective therape