https://www.selleckchem.com/products/cct128930.html This review has been carried out to inform recommendations about which questionnaires are most clinically and cost effective and valuable in contributing to the best possible management strategy for a person with tinnitus. Separate reviews focus more specifically on assessment of psychological impact and quality of life (evidence reviews F and G).Tinnitus can have an important negative impact on a person’s quality of life. It can affect how they go about their usual daily activities and impact on work, school, home and relationships as well as their mental health. The majority of tinnitus management strategies are focussed on improving the quality of life of the person living with tinnitus. Whilst the majority of management strategies available cannot permanently obliterate the tinnitus percept, they can increase acceptance of the tinnitus and improve quality of life. It is useful to assess quality of life to enable a management plan to be developed between the healthcare professional and the person with tinnitus. This review considers the most clinically and cost-effective way to assess the impact tinnitus has on quality of life. These assessments would be followed up by appropriate interventions for tinnitus and the resulting patient outcomes assessed. These assessments can also be used to record and assess progress after using the interventions described in other reviews.A number of physiological mechanisms for tinnitus have been proposed. One of these proposed mechanisms is that the perception of tinnitus is caused by abnormal synchronisation of neural activity in the central auditory nervous system. Neuromodulation aims to normalise neural activity of the auditory system, thereby reducing the perception of tinnitus. There are a variety of methods which report to use a neuromodulation approach. Neuromodulation therapies may involve the application of electrical, acoustic and/or magnetic energy to the head or ne