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https://www.selleckchem.com/products/rk-33.html In this work, the Longissimus thoracis pig skeletal muscle was used as a model to investigate the impact of two different diets, supplemented with n-3 polyunsaturated fatty acids from extruded linseed (L) and polyphenols from grape skin and oregano extracts (L+P), on the lipidomic profile of meat. A standard diet for growing-finishing pigs (CTRL) was used as a control. Changes in lipids profile were investigated through an untargeted lipidomics and transcriptomics combined investigation. The lipidomics identified 1507 compounds, with 195 compounds fitting with the MS/MS spectra of LipidBlast database. When compared with the CTRL group, the L+P diet significantly increased 15 glycerophospholipids and 8 sphingolipids, while the L diet determined a marked up-accumulation of glycerolipids. According to the correlations outlined between discriminant lipids and genes, the L diet may act preventing adipogenesis and the related inflammation processes, while the L+P diet promoted the expression of genes involved in lipids' biosynthesis and adipogenic extracellular matrix formation and functioning.Robots with the ability to actively acquire power from surroundings will be greatly beneficial for long-term autonomy and to survive in uncertain environments. In this work, a scenario is presented where a robot has limited energy, and the only way to survive is to access the energy from an unregulated power source. With no wires or resistors available, the robot heuristically learns to maximize the input voltage on its system while avoiding potential obstacles during the connection. CircuitBot is a 6 DOF manipulator capable of drawing circuit patterns with graphene-based conductive ink, and it uses a state-of-the-art continuous/categorical Bayesian Optimization to optimize the placement of conductive shapes and maximize the energy it receives. Our comparative results with traditional Bayesian Optimization and Genetic algorithms show t
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