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https://www.selleckchem.com/products/icec0942-hydrochloride.html AIM To investigate whether a combination of readily available osteoporosis screening systems, instead of dual energy X-ray absorptiometry (DXA), can aid in the identification of characteristic features of hip fracture in post-menopausal patients undergoing hemodialysis. METHODS Forty patients (58-90 years old) who had undergone quantitative ultrasound (QUS) on more than one occasion were included. Heel QUS (conducted yearly for 3 years), digital image processing (DIP), and the fracture risk assessment tool (FRAXR) were used to evaluate bone fragility. The latter two assessments (DIP and FRAXR) were conducted on 25 and 26 of the 40 patients mentioned above respectively, for this study. RESULTS Hip fractures were identified in five patients. The mean values of broadband ultrasound attenuation (BUA) and speed of sound (SOS) in patients with hip fractures were 80±7 dB/MHz and 1,491±14 m/s, respectively, while the recorded values in patients without fractures were 88±9 dB/MHz and 1,506±22 m/s, respectively. The maodialysis, the clinical importance of measuring DXA is growing, but it is necessary to estimate not only bone mass, but also bone quality. New modalities for the evaluation of bone quality are required in the future.AIM Kampo medicines containing Scutellariae Radix (the root of Scutellaria baicalensis Georgi; SR) sometimes cause serious adverse effects, including interstitial pneumonia and liver dysfunction. Baicalin (BL) is the major active component of SR and is presumed to be responsible for the adverse effects. We analyzed the amounts of BL in Kampo medicines to better understand how they can be used safely. METHODS We determined the amounts of BL in 28 Kampo decoctions containing SR (recommended daily dose 1.5-4 g/day) and corresponding Kampo extract products by high-performance liquid chromatography. RESULTS The amounts of BL in the Kampo decoctions were 1.7-4.0-fold higher than those of the

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