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https://www.selleckchem.com/products/yo-01027.html These recent developments have contributed to a more efficient and specific treatment protocol in breast cancer patients. Moreover, further investigation should be done in improving results for all the patients with breast cancer disease, particularly the individuals who have advanced breast cancer and considering the issue of drug resistance also poses threat to the successful development of targeted therapy in various subtypes of breast cancer. These recent developments have contributed to a more efficient and specific treatment protocol in breast cancer patients. Moreover, further investigation should be done in improving results for all the patients with breast cancer disease, particularly the individuals who have advanced breast cancer and considering the issue of drug resistance also poses threat to the successful development of targeted therapy in various subtypes of breast cancer.Heterocyclic compounds play a critical role in medicinal chemistry and many available drugs contain heterocyclic rings. A six-membered heterocyclic compound pyridine showed various applications that acts as an important solvent, reagent, and precursor in agrochemicals and pharmaceuticals. Due to the increase of drug resistance, there is an obvious medical need to develop new antiviral agents. Various derivatives of pyridine scaffold display abroad biological activities such as anti-microbial, anti-viral, antioxidant, anti-diabetic, anti-cancer, anti-malaria, analgesic and anti-inflammatory activities, psychopharmacological antagonistic, anti-amoebic agents, and anti-thrombic activity. Due to the high importance of pyridine derivatives, in the present review, we tried to collect and classify many pyridine derivatives based on their structures from 2000 to 2020. Pyridine derivatives were classified into two general categories including pyridine containing heterocycles and pyridine fused rings. Structure-activitd the past and present r

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