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https://www.selleckchem.com/products/brensocatib.html The occurence of Clogmia albipunctata (Diptera Psychodidae Psychodinae) has been confirmed in the territory of the Czech Republic since 2011. Although it is a non-hematophagous species of tropical origin, it presents a human health risk associated mainly with the mechanical transmission of various pathogens. In addition, C. albipunctata is one of the insects that cause accidental myiasis. The aim of this summary is to provide a comprehensive view of Clogmia albipunctata and accidental myiasis related health issues. Two case reports are presented one of drain fly larvae as a putative parasite and the other of the first passive transfer of drain fly larvae to the human body in the Czech Republic. In order to improve the surveillance of invasive pneumococcal disease (IPD), the National Reference Laboratory (NRL) for Streptococcal Infections implemented whole genome sequencing (WGS) of Streptococcus pneumoniae. This article reports the first WGS data on S. pneumoniae isolates in the Czech Republic. Thirty-five isolates of S. pneumoniae from IPD recovered in 2017-2019 were selected for WGS. These were serotypes 4, 8, 9V, 19A, and 22F, which were determined by the Quellung reaction in combination with endpoint multiplex PCR (mPCR). Multilocus sequence typing (MLST) is routinely used for more detailed analysis termed sequence typing. The selected isolates were analysed by WGS on the Illumina MiSeq platform. The sequences obtained were processed using the Velvet de novo Assembler software. The assembled genomes were uploaded into the PubMLST database, using the BIGSdbplatform, and then scanned automatically and molecularly characterized. The isolates were compared at three resolution levels seven MLST gthem to aspecific serotype. WGS has also shown its discriminatory power, allowing the assignment of isolates of the same serotype and sequence type to different genetic clusters. Of the methods used so far in the Czech Rep

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