Yam Code

New Paste Browse

https://www.selleckchem.com/products/glutathione.html Despite of their potent therapeutic implica-tions, concerns have arisen in context to their efficacy and probable clinical outcome. Thus, to overcome these glitches many heterocyclic and cyclic hydrocarbon compounds inspired by natural sources have been synthesized and showed im-proved therapeutic activity. Computational studies (molecular docking) have been used to predict the binding affinity of these natural bioactive as well as synthetic compounds derived from natural sources for the acetylcholine esterase, α/β secretase Nuclear Factor kappa-light-chain-enhancer of activated B cells(NF-kB),Nuclear factor erythroid 2-related factor 2(Nrf2) and other neurological targets. Thus, in this review, we have discussed molecular etiology of AD, focused on the pharmacotherapeutics of natural product, chemical and pharmacological aspects and multi-targeted designed ligands (MTDLs) of synthetic and semisynthetic molecules derived from the natural sources along with some important on-going clinical trials.Hepatocellular carcinoma (HCC) is the primary liver cancer that has shown a high incidence and mortality rate worldwide among several types of cancers. A large variety of chemotherapeutic agents employed for the treatment has a limited success rate owing to their limited site-specific drug targeting ability. Thus, there is a demand to develop novel approaches for the treatment of HCC. With advancements in nanotechnology-based drug delivery approaches, the chal-lenges of conventional chemotherapy have been continuously decreasing. Nanomedicines constituted of lipidic and poly-meric composites provide a better platform for delivering and open new pathways for HCC treatment. A score of nanocar-riers such as surface-engineered liposomes, nanoparticles, nanotubes, micelles, quantum dots, etc. has been investigated in the treatment of HCC. These nanocarriers are considered to be highly effective clinically for delivering chemot

Paste Settings

Paste Title : [Optional]

Paste Folder : [Optional]

Syntax Highlighting : [Optional]

Paste Expiration : [Optional]

Paste Status : [Optional]

Password : [Optional]

Description: [Optional]

Tags: [Optional]

Encrypt Paste (?)

You are currently not logged in, this means you can not edit or delete anything you paste. Sign Up or Login

Paste Settings

Site Languages