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https://www.selleckchem.com/products/climbazole.html The thermal conductivity of metal-organic frameworks (MOFs) imposes significant impacts on the thermal transfer performance of related adsorption systems in engineering applications. However, how the structural properties of MOFs affect their thermal conductivities has yet to be unraveled. In this work, the thermal conductivities of 18 zeolitic imidazolate frameworks (ZIFs) were calculated by equilibrium molecular dynamics (MD) simulations. It was revealed that the thermal conductivities of ZIFs were not directly correlated with the commonly investigated structural properties. Thus, two parameters including alignment tensor (Ai) and pathway factor (Pf) were proposed to quantitatively evaluate the orientation and distribution of heat transfer pathways within frameworks, which was demonstrated to correlate better with the thermal conductivities of ZIFs. This study provides new insights into the thermal transfer mechanism within framework-based nanoporous materials, which may also facilitate fundamental understanding and guide the rational design of porous crystals with the thermal conductivity of interest.The ability of cells to sense and respond to mechanical signals from their surrounding microenvironments is one of the key issues in tissue engineering and regeneration, yet a fundamental study of cells with both cell observation and mechanical stimulus is challenging and should be based upon an appropriate microdevice. Herein we designed and fabricated a two-layer microfluidic chip to enable simultaneous observation of live cells and cyclic stretching of an elastic polymer, polydimethylsiloxane (PDMS), with a modified surface for enhanced cell adhesion. Human mesenchymal stem cells (hMSCs) were examined with a series of frequencies from 0.00003 to 2 Hz and varied amplitudes of 2%, 5%, or 10%. The cells with an initial random orientation were confirmed to be reoriented perpendicular to the stretching direction at f

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