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https://www.selleckchem.com/products/tauroursodeoxycholic-acid.html The study results indicate that textual information from EMRs could facilitate phenotyping of ischemic stroke when this information was combined with structured information. Furthermore, decomposition of this multi-class problem into binary classification tasks followed by aggregation of classification results could improve the performance.Area under the receiver operating characteristics curve (AUC) is an important metric for a wide range of machine-learning problems, and scalable methods for optimizing AUC have recently been proposed. However, handling very large data sets remains an open challenge for this problem. This article proposes a novel approach to AUC maximization based on sampling mini-batches of positive/negative instance pairs and computing U-statistics to approximate a global risk minimization problem. The resulting algorithm is simple, fast, and learning-rate free. We show that the number of samples required for good performance is independent of the number of pairs available, which is a quadratic function of the positive and negative instances. Extensive experiments show the practical utility of the proposed method.This article proposes a real-time event-triggered near-optimal controller for the nonlinear discrete-time interconnected system. The interconnected system has a number of subsystems/agents, which pose a nonzero-sum game scenario. The control inputs/policies based on proposed event-based controller methodology attain a Nash equilibrium fulfilling the desired goal of the system. The near-optimal control policies are generated online only at events using actor-critic neural network architecture whose weights are updated too at the same instants. The approach ensures stability as the event-triggering condition for agents is derived using Lyapunov stability analysis. The lower bound on interevent time, boundedness of closed-loop parameters, and optimality of the proposed cont

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