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https://www.selleckchem.com/products/beta-aminopropionitrile.html 66 vs. 3.06 vs. 3.00 respectively, p = .043) and anti-S1RBD IgG (median OD450 2.33 vs. 1.6 vs. 0.91, respectively, p less then .001). By testing 48 subjects 6 months or above from discharge, a significant decrease of anti-NP IgG was observed (r -0.5838; p less then .0001), whereas anti-S1RBD IgG showed only a modest reduction (r -0.1507; p = .0647). Accordingly, 10 (21%) and 2 (4%) patients had a negative serological status for anti-NP and anti-S1RBD IgG, respectively; no association with clinical severity was found. IgGs against SARS-CoV-2 persisted several months after discharge, regardless of disease severity, suggesting that vaccination could be a valid strategy to fight the pandemic. The objectives were to characterize the effects of wearing face coverings on 1) acoustic speech cues, and 2) speech recognition of patients with hearing loss who listen with a cochlear implant. A prospective cohort study was performed in a tertiary referral center between July and September 2020. A female talker recorded sentences in three conditions no face covering, N95 mask, and N95 mask plus a face shield. Spectral differences were analyzed between speech produced in each condition. The speech recognition in each condition for twenty-three adult patients with at least 6 months of cochlear implant use was assessed. Spectral analysis demonstrated preferential attenuation of high-frequency speech information with the N95 mask plus face shield condition compared to the other conditions. Speech recognition did not differ significantly between the uncovered (median 90% [IQR 89%-94%]) and N95 mask conditions (91% [IQR 86%-94%]; P = .253); however, speech recognition was significantly worse in the N95 mask plus face shield condition (64% [IQR 48%-75%]) compared to the uncovered (P < .001) or N95 mask (P < .001) conditions. The type and combination of protective face coverings used have differential effects on attenua
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