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https://www.selleckchem.com/products/yap-tead-inhibitor-1-peptide-17.html 554, RMSRE = 1.55, MAE = 5.076). The precipitation values are modelled with the CanEsm2 climate change model. To apply NDVI for runoff forecasting, a simple spatial-temporal GSGMDH based model was developed (average values; SI = 0.27; RMSRE = 8.27, MAE = 0.08). The forecasting results indicated that the months in which the maximum runoff occurred have changed, and these months have increased compared to the historic period. In the historical period, the frequency of maximum runoff was in April and March. Still, for the two forecasting periods (i.e. 2020-2039 and 2040-2059), the months in which the maximum runoff has occurred have changed, and their amount has been reduced and added to other months, especially February and August.The Western Ghats (WG) mountain range in the Indian sub-continent is a biodiversity hotspot, now faces a severe threat to the valley population and ecosystem because of changing rainfall patterns and land-use changes. Here, we use the 2018-2019 landslide inventory data together with various geo-environmental factors and show that the landslide activity in the WG region is amplified by anthropogenic disturbances. We applied a generalized feature selection algorithm and a random forest susceptibility model to demonstrate the major topographic controls of landslides and the risk associated with them in the WG region. Our results show that road cutting and slopes modified to plantations are the strongest environmental variable (50% - 73% within 300 m buffer distance) related to the landslide patterns, whereas short-duration intense precipitation in the high elevated terrain, profile concavity, and stream power contributed to the initiation of landslides. The susceptibility models made for the present, and Global Climate Models (GCM) under the representative concentration pathway (RCP) 8.5 scenario predicts the vulnerable nature of WG for future climate extremes. Our result

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