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ries both for fresh consumption and as a raw material for many types of processing and freezing. As a result of the conducted studies of the chemical composition of strawberries, taking into account the technological requirements for this raw material (content of soluble solids, sugars, vitamins), the following varieties are recommended for processing Marmolada, Molling Pandora, Florence, Elsanta, Tair. Berries of the following varieties are suitable for freezing Marmolada, Alba, Arosa, Nelly, Onda, as the most fully preserving the original quality of berries, having a low juice yield and a high tasting rating. Conclusion. On the basis of the comprehensive studies of the quality of berries, promising varieties of strawberries were identified for cultivation in the south of Russia, characterized by high nutritional value, excellent taste, usage in food consumption both fresh and frozen, as well as in the production of canned products, including obtaining foodstuffs for functional purposes.Improving the quality of nutrition for children with gluten intolerance in preschool institutions is an important state task. Relevant adjustment of the diet enables to reduce the risk of the celiac syndrome. Balanced nutrient composition of diet is necessary for the harmonious growth and development of a child. The aim of the research was to develop specialized diet for children with gluten intolerance and celiac desease in municipal preschool educational institutions. Material and methods. A study of the 10-days full-day menu of children aged 3 to 7 years was carried out. To compose the specialized menu, we used the computational program "MDOU Calculate menu. Universal program for kindergarten". Technological maps of dishes in municipal preschool educational institutions were used. The calculation of the supply of the diet with vitamins, minerals and trace elements and the deviation of the nutritional and energy value of the diet from the recommended daily intake was made. Results. The necessity of developing a specialized diet for children 3-7 years old with a confirmed diagnosis of celiac disease, as well as for children on a gluten-free diet has been substantiated. A specialized daily food ration has been developed, consisting of four meals. Analysis of the nutritional and energy value of the dishes offered in the menu showed the minimum deviation of the obtained indicators from recommended daily intake. The necessity of introducing the developed diet into the system of specialized nutrition in preschool educational institutions has been substantiated. Conclusion. The results of the work indicate that under the conditions of state funding, there is a possibility of adjusting the existing food rations for the full-fledged socialization of children with various diseases.Non-alcoholic steatohepatitis (NASH) is a widespread disorder associated with a number of metabolic disorders. Lifestyle modification, including diet and physical activity are currently a first-line treatment for the disease. However, there is lack of specialized products (SP) with modified carbohydrate and fat composition, containing biologically active ingredients with proven physiological effects on the liver for this disorder. https://www.selleckchem.com/products/th5427.html The aim of the paper is to summarize present knowledge on the biologically active ingredients with proven hepatoprotective effect and to describe the process of the development of two specialized products for clinical use in patients with NASH. Material and methods. Food ingredients containing soy and milk proteins, soluble dietary fiber, mono- and polyunsaturated fatty acids, vitamins, minerals, soy lecithin, L-carnitine, coenzyme Q10, α-lipoic acid, betaine, flavoring and aromatic additives were used in the development of SP formulations. The mass fraction of moisture in the SP warapy of patients with NASH.Despite the presence of combined deficiency of vitamins D and group B among the population of Russia, the intake of cholecalciferol is often recommended without correcting the supply with B group vitamins, which are involved in ensuring the biological functions of vitamin D. The aim of the study was to compare the effectiveness of vitamin D deficit correction by replenishing its content in the diet to an adequate level without eliminating the deficit of B vitamins and by restoring vitamin D level in combination with B vitamins. Material and methods. The experiment was carried out on male Wistar rats (n=33) with an initial body weight of 69.5±0.8 g. Combined deficit of vitamins D and B group in rats (n=24) was caused by a 5-fold decrease in their content in the vitamin mixture of a semi-synthetic diet for 23 days. Over the next 7 days, in order to correct vitamin deficiency, 12 rats (group «-B+D») were fed a diet, replenished up to 100% for vitamin D with continued deficiency of B group vitamins, and 12 rats (n - by 11.7% (p less then 0.05), the activity of aspartate aminotransferase was 1.5 fold less, alanine aminotransferase - 2.3 fold (p less then 0.05), lactate dehydrogenase - by 14.9% (p less then 0.10), while the concentration of iron exceeded 2.7 times, glucose - by 15.0%, calcium - by 8.0%, creatinine - by 8.7% (p less then 0.05), urea - by 32.1%, direct bilirubin - by 24.2% (p less then 0.10 ) compared with corresponding indicator in rats of the control group. The level of cholesterol and HDL cholesterol was 14.7% and 15.9% higher (p less then 0.10) than in animals of the «+B+D» group. Conclusions. Deficiency of B vitamins inhibits the restoration of adequate supply with vitamin D. In the presence of a lack of B vitamins in rats, vitamin D deficit and its consequences cannot be completely eliminated. Adequate supply with vitamins D and B group are synergistic factors in maintaining the level of glucose, cholesterol in blood plasma and other diagnostically significant parameters.Obesity is a multifactorial disease, the prevalence of which has increased over the past few decades worldwide in all age groups. There is evidence of the pathogenetic role of vitamin D (VD) in the formation of obesity. However, there are few studies concerning the characteristics of calcium-phosphorus metabolism in obese children. Therefore, data on the prevalence of VD deficiency stratified by body mass index categories, characteristics of calcium-phosphorus homeostasis and the relationship between the concentration of parathyroid hormone (PTH) and 25(OH)D in obese children are of scientific and practical interest. The aim of the study was to assess the VD status of children, to analyze the ratio of individual biochemical markers of bone metabolism [concentration of calcium (Ca), phosphorus (P), PTH, alkaline phosphatase (ALP) activity] depending on body mass index (BMI). Material and methods. The cross-sectional (one-stage) study included 77 children with different weight and height parameters at the age from 8 to 10 years.
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