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https://www.selleckchem.com/products/kpt-330.html 28 [0.10-0.81], P=.02). In a mixed linear model adjusted for parent gender, race/ethnicity, education, and clustering by physician, trust was associated with high-quality communication (OR 3.40 [1.61-7.20], P=.001) and receipt of high-quality information (OR 2.48 [1.18-5.21], P=.02), and inversely associated with relapse or progression (OR 0.39 [0.17-0.92], P=0.03); trust increased over time (P<.0001). Most parents form trusting relationships with their children's oncologists. Physicians can foster trust through patient-centered communication and provision of high-quality information about a child's cancer. Poor outcomes such as relapse are a threat to trust. Most parents form trusting relationships with their children's oncologists. Physicians can foster trust through patient-centered communication and provision of high-quality information about a child's cancer. Poor outcomes such as relapse are a threat to trust. When children require supplemental oxygen due to acute hypoxemic respiratory distress (AHRD), manual control of the oxygen flow is often difficult and time-consuming, and carries the risk of unrecognized hypoxia and hyperoxia. To date, no automatic oxygen titration system has been developed and evaluated in spontaneously breathing children. Children between 1 month and 15 years of age receiving supplemental oxygen due to AHRD were recruited within 24 hours following the onset of the O administration in a French University Department of Paediatrics. Patients were randomized to receive either automated oxygen administration using the FreeO2 device, or conventional manual oxygen administration over a maximum period of 6 hours. Stratification was performed to classify the patients into two age groups 1 month to 2 years of age and 2 to 15 years of age. The primary outcome was % time spent within the SpO target range (92%-98%). 60 patients (30 infants, 30 children) were randomized and 55 could be analyzedn our

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