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https://www.selleckchem.com/products/purmorphamine.html Objective  To evaluate the wear of polyethylene in a Brazilian ultracongruent knee prosthesis with a rotating platform (Rotaflex, Víncula, Rio Claro, SP, Brasil). Methods  We used the test method with the loading and preparation parameters mentioned in the standards regulation ISO 14243-12009 , and the measurement methods mentioned in the standards regulation ISO 14243-22009 , for the evaluation of the wear behavior of a Brazilian prosthesis with a rotating platform. The equipment used for the wear test was the ISO 14243-1 gait simulator (EndoLab, Riedering, Germany). Results  After 10 million cycles, the evaluation of the polyethylene wear showed a regular appearance of surface wear at a mean rate of 2.56 mg per million cycles. Conclusion  The wear of the polyethylene of the evaluated prosthesis was minimal after the tests performed and with safety limits higher than those recommended by biomechanical engineering.Objective  To virtually prototype a device for external circular fixation of long bone fractures with controlled dynamization made of two different materials and predict their mechanical behavior by using the finite element analysis (FEA) method. Method  A software was used for 3D modeling two metal parts closely attached by a sliding dovetail joint and a high-density silicone damper. Distinctive FEAs were simulated by considering two different materials (stainless steel or titanium), modes (locked or dynamized) and loading conditions (static/point or dynamic/0.5 sec) with uniform 150 kg axial load on top of the device. Results  The finite elements (FEs) model presented 81,872 nodes and 45,922 elements. Considering stainless steel, the maximum stress peak (140.98 MPa) was reached with the device locked under static loading, while the greatest displacement (2.415 × 10 -3 mm) was observed with the device locked and under dynamic loading. Regarding titanium, the device presented the maximum stress peak (

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