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https://www.selleckchem.com/products/thz531.html The intention to be screened for AD could serve public awareness by defining effective ways to assist older adults to seek a cognitive screen.Renal cell carcinoma (RCC) is the most common malignancy to cause metastasis to sinonasal cavity. These metastases can occasional cause invasion into the orbit. Isolated intraconal intraorbital metastasis from RCC is very rare. We hereby describe a case of 72-year-old female, who underwent right nephrectomy for RCC, 8 years back, and now presenting with a space occupying lesion in the right intraorbital intraconal compartment with no involvement of the paranasal sinuses. En bloc resection of the tumor was achieved via transnasal endoscopic approach. This is a rare case where minimally invasive surgery was done for metastatic lesion, with minimal postoperative morbidity.Chondrosarcoma of nasal cavity is a rare entity, and only few case reports exist. Diagnosis is made on histopathological analysis. Differentiating chondrosarcoma from chondromas can be challenging. Surgical excision remains the treatment of choice. We report a case of a 73-year-old male who presented to us with complaints of bilateral nasal obstruction. Histopathology reported as moderately differentiating chondrosarcoma. Patient subsequently underwent excision of tumor by craniofacial resection with adjuvant radiotherapy. Patient is on regular follow-up and has shown no evidence of recurrence.Gastric cancer perforations are rare events with management options ranging from lavage and perforation closure, to resection. Usual aim is to perform a damage control procedure, and very few patients are suitable for a curative resection. We report the first case of emergency gastrectomy with pancreatico-duodenectomy performed in emergency for a perforated stomach cancer with pancreatic head invasion. The patient was a 32-year-old gentleman who presented with a perforated antro-pyloric cancer with infiltration of pancreatic

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