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https://www.selleckchem.com/GSK-3.html It had better antimicrobial activity against Bacillus subtilis than a commonly-used antibiotic, tetracycline. Furthermore, B14 broth could inhibit the growth of a tetracycline-resistant Serratia marcescens. Our results showed promising B14 BS applications not only for bioremediation but also for the production of antimicrobial products.The constructing laborers are mainly unskilled, untrained, migrant, socially backward, and uneducated with low bargaining power. Thus, we assessed the knowledge and prevalence on occupational safety and health (OSH) of laborers working at private constructing sites. A descriptive cross-sectional study of 229 laborers working at private constructing sites selected by 30 cluster sampling methods from the Lalitpur metropolitan city and Mahalaxmi municipality was conducted using a structured questionnaire and observation checklist. EpiData and SPSS were used for data analysis. Most of the laborers (62%) had inadequate knowledge on OSH. The level of knowledge was significantly associated with sex, education, and family type at 95% CI (p value  less then  0.05). The prevalence of occupational accidents within a year was 19.7% and was significantly associated with the use of Personal Protective Equipment (PPE) at 95% CI (p value  less then  0.05). About one-fifth of the participants had occupational accidents within a year because of the inadequate knowledge of OSH.Zoonotic diseases have devastating impacts on human and animal health, livelihoods, and economies. Addressing the complex web of interrelated factors leading to zoonotic disease emergence and spread requires a transdisciplinary, cross-sectoral approach, One Health. The One Health approach, which considers the linkages between the health of people, animals, and their shared environment, presents opportunities to reduce these impacts through a more holistic coordinated strategy to understanding and mitigating disease risks. Understanding the li

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