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https://www.selleckchem.com/products/mki-1.html Carbohydrate recognition is established as a property of lectins and implicated in many functions including immunity and defense against pathogens. Many lectins are characterized and proposed for various applications owing to the above said recognition. The crystal structure of a lectin from Pleurotus ostreatus has been determined and shown to be calcium dependent. The overall structure is a tandem repeat of two β-jelly roll domains, a new fold for lectins. The calcium dependence of sugar binding is analyzed in-detail through isothermal titration calorimetry. The serendipitous observation of malonate and glycerol, the intentional N-Acetyl-D-galactosamine, D-Galactose and L-Rhamnose binding to Pleurotus ostreatus lectin by Ca2+ coordination revealed that the binding site is promiscuous. Among these sugars, Rhamnose binding found to be thermodynamically most favourable. In all these structures, a vicinal diol motif, one at axial and the other at equatorial positions could be established as a specific requirement for binding. Interestingly, when compared with other calcium mediated lectin structures; this geometric requirement is found conserved. This observation could lead to the conclusion that lectins are not 'molecule specific' but 'geometry specific' so that any molecule not necessarily a sugar may be recognized by this lectin if the geometry exists. The Coats-Redfern method is commonly used to calculate the activation energy of the thermal degradation from a single non-isothermal thermogravimetric curve since its first proposal in 1964. This paper represents the accurate expressions, sound derivation process and proper usage of the Coats-Redfern equations, based on the critique into the Coats-Redfern's original article, Djalal Trache's incorrect comments on Reza Arjmandi et al.'s article, and the flaw in Reza Arjmandi et al.'s work per se. The need for starch to meet the ever-increasing industrial applications and i
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