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https://www.selleckchem.com/products/ly2801653-merestinib.html Because studies have suggested that atropine might slow the progression of myopia in children, randomized clinical trials are warranted to understand this potential causal relationship. To evaluate the efficacy and safety of atropine, 0.01%, eyedrops on slowing myopia progression and axial elongation in Chinese children. This was a randomized, placebo-controlled, double-masked study. A total of 220 children aged 6 to 12 years with myopia of -1.00 D to -6.00 D in both eyes were enrolled between April 2018 and July 2018 at Beijing Tongren Hospital, Beijing, China. Cycloplegic refraction and axial length were measured at baseline, 6 months, and 12 months. Adverse events were also recorded. Patients were randomly assigned in a 11 ratio to atropine, 0.01%, or placebo groups to be administered once nightly to both eyes for 1 year. Mean changes and percentage differences in myopia progression and axial elongation between atropine, 0.01%, or placebo groups. Of 220 participants, 103 were girls (46.8%), andannot be determined from this trial, these 1-year results, limited by approximately 70% follow-up, suggest that atropine, 0.01%, eyedrops can slow myopia progression and axial elongation in children and warrant future studies to determine longer-term results and potential effects on slowing sight-threatening pathologic changes later in life. http//www.chictr.org.cn Identifier ChiCTR-IOR-17013898. http//www.chictr.org.cn Identifier ChiCTR-IOR-17013898. Parents often provide advice to their adult children during their everyday interactions. This study investigated young adult children's daily experiences with parental advice in U.S. families. Specifically, the study examined how receiving advice and evaluations of parental advice were associated with children's life problems, parent-child relationship quality, and daily mood. Young adult children (aged 18-30; participant N = 152) reported whether they received any

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