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https://www.selleckchem.com/products/BI6727-Volasertib.html 748 - 0.925). When the cutoff was 4.746, the sensitivity and specificity were 86.9% and 91.5%, respectively. More importantly, peripheral blood miR-148 combined with ESR and hs-CRP demonstrated better diagnostic efficiency in active UC patients. Conclusions In summary, enhanced expression of miR-148 in peripheral blood of UC patients may be expected to be an index for evaluating the activity of UC disease.Background The objective of this study is to investigate the correlation of mean platelet volume (MPV), MPV/ platelet count, and monocyte to lymphocyte ratio (MLR) between cervical cancer patients and healthy people and to evaluate the value of those parameters in early diagnosis of cervical cancer. Methods The study population included 137 cervical cancer patients undergoing hysterectomy and 113 healthy controls. The clinical features (age, pathology type, tumor staging, and tumor size) were collected from the hospital information system. The hematology parameters (white blood cell, red blood cell, hemoglobin, platelet count, neutrophil, lymphocyte, monocyte, mean platelet volume, platelet distribution width) are obtained in the laboratory information system. Results We found that the monocyte count and MLR value are higher in the cervical cancer group. The MPV and MPV/platelet are lower in the cervical cancer group. The receiver operating characteristic (ROC) analysis shows that MPV+MLR can generate a moderate specificity with 71.68%, sensitivity with 65.69%, and AUC with 0.718 to distinguish cervical cancer and healthy people. Conclusions MPV/platelet and MLR may be helpful for the early diagnosis of cervical cancer. A larger clinical data analysis is necessary to evaluate the diagnostic value of hematologic parameters in cervical cancer.Background Anemia is one of the most common hematological problems in HIV infected patients in the world. The main aim of this study was to determine the magnitude of a

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