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https://www.selleckchem.com/products/filgotinib.html Physical fitness (PF) and physical activity (PA) are inversely associated with body mass index and waist circumference (WC), whereas sedentary time (ST) seems to boost obesity in youth. The aim was to examine the associations of each selected PF test, PA-related exposures, and specific ST patterns with obesity and determine the most relevant ones, in a large sample of a school-aged adolescent. The sample consisted of 2696 Portuguese youth aged 10 to 18 years. Height, weight, and WC were measured. PA and ST components were measured using accelerometry. PF was evaluated using a battery of tests. The Progressive Aerobic Cardiovascular Endurance Run (PACER) and push-up tests seemed to be the exposures that presented the strongest and more consistent associations with obesity, independent of PA/ST profiles (P < .05). The second exposure of relevance for adolescent obesity level was the breaks in ST with a negative relationship regardless of PA/PF profiles (P < .05). Finally, ST accumulated in periods of <30 minutes, and moderate-to-vigorous PA were favorably associated with obesity, independent of ST/PF. Independent of PA and ST, cardiorespiratory fitness (CRF), measured by PACER, was associated with obesity markers. This may be in part due to the dependence of PACER performance on adiposity. Also, limiting prolonged ST and promoting interruptions in this behavior were associated with obesity. These associations suggest that future research should examine other strategies beyond PA promotion for tackling obesity that consider CRF and breaking ST. Independent of PA and ST, cardiorespiratory fitness (CRF), measured by PACER, was associated with obesity markers. This may be in part due to the dependence of PACER performance on adiposity. Also, limiting prolonged ST and promoting interruptions in this behavior were associated with obesity. These associations suggest that future research should examine other strategies beyo

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