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https://www.selleckchem.com/products/emd638683.html BACKGROUND We evaluated the association of antiretroviral therapy (ART), CD4+ count and HIV plasma viral load (PVL) on high-grade cervical intraepithelial neoplasia (CIN2+) detection at follow-up after CIN management among women living with HIV (WLHIV). METHODS Medline, Embase, Global Health and PubMed were searched from January 1, 1996 to January 15, 2020. Eligible studies investigated the association of ART, CD4+ count or HIV PVL on histology-confirmed CIN2+ detection at follow-up. Summary estimates were obtained using random-effects meta-analyses; heterogeneity was examined using I2 statistic. PROSPERO registrationCRD42018115631. RESULTS Eight studies representing 9 populations were identified, including 1,452 WLHIV followed between 6 to 33 months post-CIN management. Pooled data from 8 populations (n=1,408) suggested weak evidence of a decreased risk of CIN2+ detection at follow-up among ART users compared to ART-naïve women (crude odds ratio [cOR]=0.70, 95% CI 0.36-1.36; I2=64.5%, p=0.006; adjusted risk findings support recommendations of early ART and the integration of CIN2+ screening and management into HIV care. © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.BACKGROUND Although kidney transplantation prolongs survival relative to dialysis, it is associated with a higher death rate than in the general population. The objective of the present study was to assess and compare the risk of mortality and frequency of non-lethal cardiovascular (CV) events in kidney transplant recipients (KTRs) beyond 1 year after successful transplantation versus patients with chronic kidney disease (CKD) using propensity score-matched analysis of estimated glomerular filtration rate (eGFR) and other parameters. METHODS After propensity score matching, we studied 340 KTRs from the French Données Inf

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