Yam Code
Sign up
Login
New paste
Home
Trending
Archive
English
English
Tiếng Việt
भारत
Sign up
Login
New Paste
Browse
The median [IQR; range] pressure gradient change after initiation of GA was -3 [-12, 0; -22, 9] mmHg (p = 0.014). After correction for increases in internal jugular vein (IJV) pressures associated with assumption of GA, the median [IQR; range] gradient change was -11 [-12.5, -5; -22, 0] mmHg (p less then 0.001). CONCLUSION The transition from CS to GA, results in clinically meaningful reductions in transverse sinus gradients in IIH. Correction for increases in the IJV pressures reveals even more dramatic reductions in transverse sinus gradients. BACKGROUND VerifyNow® directed personalized antiplatelet therapy for aneurysm embolization with a Pipeline embolization device (PED) remains controversial. OBJECTIVE Evaluate thrombotic complications between patients who received VerifyNow® directed personalized antiplatelet therapy versus those who did not following PED flow-diversion of complex cerebral aneurysms. METHODS Retrospective cohort of consecutive patients undergoing flow-diversion with PED at the Medical University of South Carolina (MUSC) between January 2012 to May 2018. Patients who received VerifyNow® directed personalized antiplatelet therapy were compared to those who received antiplatelet therapy without platelet function testing. Patients with a P2Y12 reaction unit (PRU) ≥ 194 were deemed to be clopidogrel hyporesponsive. The primary outcome is the rate of thrombotic complications and the secondary outcomes are the rate of hemorrhagic and thrombotic complications stratified by PRU and high-risk clinical and procedure-related candidate predictors. RESULTS Thrombotic complications were not different between patients managed with (n = 159) vs without (n = 110) VerifyNow® (6.9% vs 7.3%; p=0.911). https://www.selleckchem.com/products/ga-017.html Hemorrhagic complications were also no different (3.1% vs 4.5%; p=0.550). PRU stratification revealed no difference in thrombotic or hemorrhagic complications (p=0.488 and p=0.136, respectively). The only significant predictors for thrombotic complications were the presence of diabetes (OR 2.9; p=0.034), obesity (OR 5.1; p= less then 0.001), fusiform aneurysm (OR 3.3; p=0.023), posterior circulation implantation (OR 3.4; p=0.016), and more than one PED implanted (OR 2.4; p=0.046). CONCLUSION The role of VerifyNow® and personalized antiplatelet therapy in patients undergoing flow diversion with PED to treat complex aneurysms did not demonstrate a benefit in reducing thrombotic complications. OBJECTIVE The aim of this study was to evaluate the radiological outcomes and complication analysis of posterior vertebral column resection (PVCR) performed on previously operated severe kyphoscoliosis (SK) patients. METHODS Twelve patients (6 males, 6 females) with SK underwent PVCR. The mean age of the patients preoperatively was 16 years (range, 10-26). The mean follow-up period was 5.3 years (range, 2-7). Previous surgeries included posterior growth arrest in three patients, hemivertebrectomy in four patients and posterior fusion in five. The sagittal plane parameters and coronal parameters were measured in the preoperative, early postoperative and during the last follow-up stages. Complications were also noted. RESULTS The mean thoracic scoliosis Cobb angle was 76.8° (range, 35°-142°) preoperatively, 37.8° (range 5°-80°) early postoperatively and 41.5° (range, 11°-80°) during the last follow-up (p less then 0.0001). The mean thoracic kyphosis angle was 84.7° (range, 23°-132°) preoperatively, 50.3° (range, 25°-78°) early postoperatively and 48.5° (range, 25°-80°) during the last follow-up (p=0.0032). Complications occurred in five patients (41.7%); a hemothorax in one patient, rod fracture in three patients and permanent neurological deficit in one. Temporary loss of Neuromonitoring Motor Evoked Potential developed in two patients during deformity correction. CONCLUSION PVCR provides effective correction in SK patients. However, expected surgical correction of a deformity may not always be achieved due to intraoperative neuromonitoring changes. Furthermore, PVCR can lead to a large number of major complications in SK patients who have undergone previous spinal surgery. Sphenocavernous meningioma are technically challenging tumors that, in addition to cavernous sinus neurovascular involvement, frequently affect the optic nerve and carotid artery. The surgical goal generally consists of complete resection of the extracavernous portion of the tumor, while the cavernous sinus tumor can be treated with postoperative radiation if necessary. Traditional techniques include the pterional or orbitozygomatic approach that requires substantial soft tissue, scalp, and temporalis muscle mobilization along with temporal and frontal lobe manipulation. A keyhole craniotomy performed through a lateral orbitotomy provides a minimally invasive option with excellent tumor exposure that obviates the need for soft tissue trauma or brain manipulation. Use of an endoscope can provide further visualization for more expansive tumors. This video presentation demonstrates a case of an 84 year-old female with a growing sphenocavernous meningioma and abducens palsy who underwent a minimally invasive lateral orbital wall approach for resection of the extracavernous tumor. There were no intraoperative or perioperative complications and the patient was discharged home on postoperative day 1. This technique is a useful addition to the armamentarium of surgeons who treat these complex tumors. Proteus syndrome (PS) is a complex genetic disorder, characterized by the sporadic appearance of hamartomatous lesions that follow a mosaic pattern and have a progressive evolution. It affects most of the mesodermal origin tissues, including the bone. Scoliosis is a common manifestation, with great variability and specific peculiarities, but little has been published about it. PURPOSE Presentation of 2 clinical cases of patients with PS that underwent scoliosis surgery and literature review. METHODS Two 17-year-old's, a female (Patient 1) and a male (Patient 2), both diagnosed of PS, were being followed-up for scoliosis. Patient 1 had a right thoracic curve with a Cobb angle (CA) of 69,1º, while patient 2 had, as well, a right thoracic curve of 106,8º. In both patients a posterior fusion was performed, associating rib and ponte osteotomies at the level of the apex in patient 2. A minimum 2-year follow-up was done. RESULTS Both patients had a satisfactory evolution without neurological or other complications, with a high degree of correction of their curves (CA 29,2º and 55,6º respectively).
Paste Settings
Paste Title :
[Optional]
Paste Folder :
[Optional]
Select
Syntax Highlighting :
[Optional]
Select
Markup
CSS
JavaScript
Bash
C
C#
C++
Java
JSON
Lua
Plaintext
C-like
ABAP
ActionScript
Ada
Apache Configuration
APL
AppleScript
Arduino
ARFF
AsciiDoc
6502 Assembly
ASP.NET (C#)
AutoHotKey
AutoIt
Basic
Batch
Bison
Brainfuck
Bro
CoffeeScript
Clojure
Crystal
Content-Security-Policy
CSS Extras
D
Dart
Diff
Django/Jinja2
Docker
Eiffel
Elixir
Elm
ERB
Erlang
F#
Flow
Fortran
GEDCOM
Gherkin
Git
GLSL
GameMaker Language
Go
GraphQL
Groovy
Haml
Handlebars
Haskell
Haxe
HTTP
HTTP Public-Key-Pins
HTTP Strict-Transport-Security
IchigoJam
Icon
Inform 7
INI
IO
J
Jolie
Julia
Keyman
Kotlin
LaTeX
Less
Liquid
Lisp
LiveScript
LOLCODE
Makefile
Markdown
Markup templating
MATLAB
MEL
Mizar
Monkey
N4JS
NASM
nginx
Nim
Nix
NSIS
Objective-C
OCaml
OpenCL
Oz
PARI/GP
Parser
Pascal
Perl
PHP
PHP Extras
PL/SQL
PowerShell
Processing
Prolog
.properties
Protocol Buffers
Pug
Puppet
Pure
Python
Q (kdb+ database)
Qore
R
React JSX
React TSX
Ren'py
Reason
reST (reStructuredText)
Rip
Roboconf
Ruby
Rust
SAS
Sass (Sass)
Sass (Scss)
Scala
Scheme
Smalltalk
Smarty
SQL
Soy (Closure Template)
Stylus
Swift
TAP
Tcl
Textile
Template Toolkit 2
Twig
TypeScript
VB.Net
Velocity
Verilog
VHDL
vim
Visual Basic
WebAssembly
Wiki markup
Xeora
Xojo (REALbasic)
XQuery
YAML
HTML
Paste Expiration :
[Optional]
Never
Self Destroy
10 Minutes
1 Hour
1 Day
1 Week
2 Weeks
1 Month
6 Months
1 Year
Paste Status :
[Optional]
Public
Unlisted
Private (members only)
Password :
[Optional]
Description:
[Optional]
Tags:
[Optional]
Encrypt Paste
(
?
)
Create New Paste
You are currently not logged in, this means you can not edit or delete anything you paste.
Sign Up
or
Login
Site Languages
×
English
Tiếng Việt
भारत