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https://www.selleckchem.com/products/dup-697.html 6% were K. oxytoca and the rest were K. pneumoniae. Disc diffusion showed that 21 (8.4%) isolates were MDR, 19 (90.4%) of which were ESBL producers including one K. oxytoca. The most prevalent β-lactamase gene was blaSHV followed by blaTEM and blaCTX-M , but blaOXA-48 , blaKPC , and blaNDM were not detected. Class 1 integron was detected in 18 out of 21 MDR isolates (85.7%), but classes 2 and 3 were not observed. Two isolates were resistant to carbapenems and harbored blaSHV , blaTEM , and blaCTX-M , as well as class 1 integron. Conclusion ESBL production and the presence of multiple β-lactamase genes in MDR community isolates of Klebsiella spp. can have significant implications in terms of the spread of these opportunistic pathogens. Copyright © Shiraz University of Medical Sciences.Background Vision plays an important role in supporting efficient locomotion. The present study aimed to measure the physiological cost index (PCI) and some kinematic parameters of preferred walking and jogging in blind and sighted students. Methods A cross-sectional study was conducted among blind (n=18) and sighted (n=27) students aged 8-16 years. The following parameters were measured during a standard test procedure step length (meter), cadence (steps/min), mean speed (meter/min), and the PCI of preferred walking (PCIW) and jogging (PCIJ) over a distance of 100 meters. Results Univariate linear regression analysis revealed that the weight of an individual as well as the test duration were significant predictors of heart rate (HR) and PCI. Overall, the PCI (beats/meter) of sighted (PCIW=0.22±0.08 and PCIJ=0.24±0.07) and blind students (PCIW=0.27±0.07 and PCIJ=0.31±0.08) were significantly different (all P≤0.05). In addition, the speed of preferred walking (PW) in sighted students was significantly higher than that of the blind students (67±8 versus 62.8±9 m/min; all P≤0.05), while this difference was insignificant in jogging mode (105

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