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https://www.selleckchem.com/pharmacological_epigenetics.html This study aimed to identify the sexual information requirements and related factors according to gender to improve sexual health in cancer patients. In this cross-sectional study, a total of 687 cancer patients from a single cancer center in Korea completed a self-reported questionnaire. Multiple logistic regression analysis was used to compare the sexual information requirements and related factors among cancer patients. The results showed that male cancer patients had higher demands for sexual information than female cancer patients (t = 27.11, p less then 0.001). Men appeared to have a greater need than women in the need for sexual information (t = 30.41, p less then 0.001) and professional sexual intervention (t = 21.97, p less then 0.001). Regarding sexual information needs, income (OR 0.43, 95% CI 0.25 to 0.73) was a significant factor in men. In women, age (OR 0.51, 95% CI 0.31 to 0.86), alcohol consumption (OR 1.88, 95% CI 1.12-3.16), and chemotherapy (OR 1.87, 95% CI 1.12-3.12) were significant factors. Significant differences in the overall sexual information needs and related factors were observed between male and female cancer patients. Therefore, a strategy needs to be established to improve the sexual health of cancer patients considering gender differences.The alkaline milieu of chronic wounds severely impairs the therapeutic effect of antibiotics, such as rifampicin; as such, the development of new drugs, or the smart delivery of existing drugs, is required. Herein, two innovative polyelectrolyte nanoparticles (PENs), composed of an amphiphilic chitosan core and a polycationic shell, were synthesized at alkaline pH, and in vitro performances were assessed by 1H NMR, elemental analysis, FT-IR, XRD, DSC, DLS, SEM, TEM, UV/Vis spectrophotometry, and HPLC. According to the results, the nanostructures exhibited different morphologies but similar physicochemical properties and release profiles.

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