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https://www.selleckchem.com/products/kg-501-2-naphthol-as-e-phosphate.html 6-109.1%) and indirect detection of glucose make the probe XH-2 a superior probe. Based on its low cytotoxicity, the probe was successfully applied to monitor endogenous/exogenous hydrogen peroxide and quantitatively determine the concentration level of hydrogen peroxide at a range of 0-120 μM (R2 = 0.9859) in HepG2 cells. Ultimately, the probe could effectively monitor the level of hydrogen peroxide during DILI in HepG2 cells.In the present work, a capture DNA (c-DNA) was immobilized on the TNA/g-C3N4 to develop a sensitive and selective TNA/g-C3N4/c-DNA photoelectrochemical aptasensor for determining thrombin. With the aid of the specific recognition of anti-thrombin aptamer towards thrombin, ingenious design of hairpin DNA, and exonuclease III-assisted recycling signal amplification, more nanoceria could be assembled on the TNA/g-C3N4/c-DNA to form TNA/g-C3N4/nanoceria in the presence of thrombin. Due to the oxidase-mimic catalytic efficiency of nanoceria and the oxygen consumption for glucose oxidation, the photoexcited electrons at the conduction band of g-C3N4 could be well transferred to that of TNA under visible light irradiation, resulting in the increase of the photocurrent of TNA/g-C3N4/nanoceria, and the increase value of photocurrent had a linear relationship with the concentration of thrombin under the optimal conditions. So, the constructed TNA/g-C3N4/c-DNA photoelectrochemical aptasensor exhibited a satisfactory quantitative range from 0.01 pM to 0.5 nM, low detection limit with 3.4 fM for thrombin determination, and was applied for the human serum analysis successfully with RSD of less than 4.8% and the recovery between 95% and 113%.Micro-tip-based solid-phase microextraction is considered as one of the green and powerful analytical sample preparation techniques, but its efficiency is severely hampered by some basic issues such as tedious fabrication, instability of sorbent b
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