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https://www.selleckchem.com/products/yum70.html Relational morphology (RM) is a novel approach to word structure that bears a close relation to construction grammar (CxG). Based on the parallel architecture framework, its basic question is what linguistic entities are stored in long-term memory, and in what form? Like CxG, RM situates the "rules of grammar" in an extended lexicon, right along with words, multiword expressions such as idioms and collocations, and meaningful syntactic constructions. However, its notion of schema enriches CxG's notion of construction in a number of respects, including (a) the possibility of purely formal schemas that lack meaning, (b) a more precise way of specifying relations among lexical items than standard inheritance, (c) the possibility of "horizontal" relations between individual words and between schemas, (d) a clearer characterization of the distinction between productive and nonproductive phenomena, and (e) more explicit integration with theories of language processing and of other domains of cognition.Gene therapy is proving to be an effective approach to treat or prevent ocular diseases ensuring a targeted, stable, and regulated introduction of exogenous genetic material with therapeutic action. Retinal diseases can be broadly categorized into two groups, namely monogenic and complex (multifactorial) forms. The high genetic heterogeneity of monogenic forms represents a significant limitation to the application of gene-specific therapeutic strategies for a significant fraction of patients. Therefore, mutation-independent therapeutic strategies, acting on common pathways that underly retinal damage, are gaining interest as complementary/alternative approaches for retinal diseases. This review will provide an overview of mutation-independent strategies that rely on the modulation in the retina of key genes regulating such crucial degenerative pathways. In particular, we will describe how gene-based approaches explore the use o

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