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https://www.selleckchem.com/products/tepp-46.html Results demonstrated that oxytocin was not effective at improving behavioral or subjective indicators of social affiliation. This study adds to a growing literature that the prosocial effects of oxytocin in schizophrenia are limited or null. Women with advanced HER2- breast cancer have limited treatment options. Breast MRI functional tumor volume (FTV) is used to predict pathologic complete response (pCR) to improve treatment efficacy. In addition to FTV, background parenchymal enhancement (BPE) may predict response and was explored for HER2- patients in the I-SPY-2 TRIAL. Women with HER2- stage II or III breast cancer underwent prospective serial breast MRIs during four neoadjuvant chemotherapy timepoints. BPE was quantitatively calculated using whole-breast manual segmentation. Logistic regression models were systematically explored using pre-specified and optimized predictor selection based on BPE or combined with FTV. A total of 352 MRI examinations in 88 patients (29 with pCR, 59 non-pCR) were evaluated. Women with hormone receptor (HR)+HER2- cancers who achieved pCR demonstrated a significantly greater decrease in BPE from baseline to pre-surgery compared to non-pCR patients (odds ratio 0.64, 95% confidence interval (CI) 0.39-0.92, l sample size limiting ability to create subtype-specific multivariate models.Artificial intelligence (AI) is a branch of computer science dedicated to developing computer algorithms that emulate intelligent human behavior. Subfields of AI include machine learning and deep learning. Advances in AI technologies have led to techniques that could increase breast cancer detection, improve clinical efficiency in breast imaging practices, and guide decision-making regarding screening and prevention strategies. This article reviews key terminology and concepts, discusses common AI models and methods to validate and evaluate these models, describes emerging AI applications in breast imaging,

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