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https://www.selleckchem.com/products/cathepsin-Inhibitor-1.html On rare occasions, differentiated thyroid carcinoma causes tumor thrombosis in the great veins. Multimodality treatment with surgery, radioiodine therapy, and targeted therapies is used to manage tumor thrombosis associated with thyroid malignancies, though no established guidelines exist. We present a woman with a tracer-avid tumor thrombus in the right brachiocephalic vein after surgery for follicular thyroid carcinoma. Follow-up revealed an excellent response after treatment with 131I as a single modality for both remnant and tumor thrombus.Previous reports suggest that a headrest significantly influences anterior and posterior cerebral blood flow. The present study aimed to clarify the influence of a headrest on reconstruction and attenuation correction (AC) of brain SPECT images. Methods We evaluated the influence on cerebral blood flow in the anterior region (brain segments A + B), middle region (segments D + F), and posterior region (segment G) of the brain using filtered backprojection-AC based on the method of Chang (FBP-ChangAC), ordered-subset expectation maximization-ChangAC (OSEM-ChangAC), OSEM CT-based AC (OSEM-CTAC), and OSEM with no attenuation correction (OSEM-NoAC) with and without a headrest. The subjects were 17 healthy volunteers who underwent 99mTc-ECD SPECT. We compared the A + B/G and the D + F/G ratios of 99mTc-ECD SPECT images in each group. Results For FBP-ChangAC, OSEM-ChangAC, and OSEM-NoAC, there were significant differences in A + B/G ratio between images obtained with a headrest and those obtained without. On the other hand, for OSEM-CTAC, there were no significant differences in A + B/G ratio regardless of whether a headrest was used. For FBP-ChangAC and OSEM-NoAC, there were significant differences in D + F/G ratio between images with a headrest and those without. For OSEM-CTAC and OSEM-ChangAC, there were no significant differences in D + F/G ratio regardless of whethe

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