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https://www.selleckchem.com/products/geneticin-g418-sulfate.html PURPOSE Improved oral health of children is noted in most Western countries, but this coincides with a high burden of oral disease in several countries of Central and Eastern Europe. The purpose of the present study was to describe the current level of dental caries in Hungarian children aged 5, 6, and 12 years and to assess the long-term trends in caries over 30 years. In addition, the report aims to highlight the oral health habits of 12-year-old children in Hungary. MATERIALS AND METHODS A representative survey was undertaken in 2016-2017 according to the WHO Pathfinder methodology, which was also applied in previous national oral health surveys of 1985, 1991, 1996, 2001, and 2008. Children of 5-6 and 12 years were sampled systematically in all surveys over 30 years. Data were gathered through clinical examinations and a questionnaire used for 12-year-olds. RESULTS In 2016-2017, 42.6% of 5- to 6-year-olds were caries free, with the proportion lower in rural than urban settings. Approximately four primary tyear-olds by the year 2020. For better oral health of children, strong emphasis should be given to population-directed oral disease prevention, including the reduction of sugar consumption and implementing public health programmes for the effective use of fluoride.PURPOSE Periodontal disease is a chronic inflammatory disease characterised by the infiltration of inflammatory cells as well as activation of pathological angiogenesis in gingival tissues. Vascular endothelial growth factor (VEGF) plays a statistically significant role in the regulation of angiogenesis and induction of an inflammatory response in periodontal tissues. MATERIALS AND METHODS We examined the association between the VEGFA gene rs699947 polymorphism and periodontal disease. This study enrolled 200 patients with periodontal disease (130 non-smokers and 70 smokers) and 160 control subjects (126 non-smokers and 34 smokers). RESUL

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