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https://www.selleckchem.com/products/sm-102.html Idiopathic adulthood ductopenia (IAD) is a chronic small duct cholestatic biliary disease that is characterized by the loss of interlobular bile ducts. It is diagnosed when there is biochemical evidence of cholestatic liver disease, ductopenia on liver biopsy, and no other identifiable cause of cholestasis. We present a patient with 10 days of progressive abdominal pain, jaundice, and worsening liver function tests who advanced to fulminant liver failure with no apparent underlying cause. He was found to have cirrhosis, with biopsy demonstrative of ductopenia, consistent with idiopathic adulthood ductopenia, which is a rare etiology of cirrhosis but should be considered when the typical workup yields no answer. © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.Achalasia is an esophageal motility disorder characterized by a lack of peristalsis and an increased lower esophageal sphincter pressure that does not relax with swallowing. High-resolution manometry (HRM), a valuable diagnostic tool for esophageal disorders, often comes with software for automated study interpretation. Although helpful, there are certain caveats in the diagnostic criteria for achalasia which the software may miss. We highlight 2 patients in whom software analysis of HRM studies resulted in misdiagnosis of achalasia as manometrically detected nonachalasia esophagogastric junction outflow obstruction and emphasize the importance of manual interpretation of HRM data by clinicians. © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.Eosinophilic enterocolitis is a rare condition representing the least frequent manifestation of eosinophilic gastrointestinal disorders. We report a 49-year-old man who presented with abdominal pain, diarrhea, and intractable vomiting for 2 weeks. Abdominal computed tomography demonstrated

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