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https://www.selleckchem.com/products/vu0463271.html DRZ-CS-PCL-NPs exhibited 3.7 fold higher mucoadhesive strength compared to the control. Furthermore, the histopathological assessment and HET-CAM study revealed that the DRZ-CS-PCL-NPs were non-irritant and safe for ocular administration. Therefore, from the present study, it can be concluded that the optimized DRZ-CS-PCL-NPs are safe and have the potential for successful ocular delivery and improved therapeutic efficacy.In the present study, two pH-sensitive bilayer films were developed and compared. Agar matrix incorporated with ZnO nanoparticles (NPs) or TiO2 NPs were combined with the infrastructure of a κ-carrageenan-Clitoria ternatea Linn anthocyanin (CA-CTLA) layer, denoted as AG-ZnO/CA-CTLA film and AG-TiO2/CA-CTLA film, respectively. The CA-CTLA layer was defined as the sensing layer, whereas the AG-TiO2 (or AG-ZnO) layer was the protective layer that enhanced the mechanical properties and colour stability. The AG-TiO2/CA-CTLA film displayed superior UV-vis light barrier property, pH sensitivity, and physical properties. The film's elongation at break and water vapour permeability were 57.08%, and 2.72 × 10-6 g.m-1.h-1.pa-1, respectively. Notably, the AG-TiO2/CA-CTLA film possessed the highest UV-vis light barrier properties, and the transmittance was close to 0 in the UV region. Furthermore, these films exhibited visual colour changes in the buffer solution (pH 2.0-12.0), ammonia vapour (80 M), and pork spoilage trials. Therefore, the bilayer films have promising properties for food packaging, especially the AG-TiO2 NPs/CA-CTLA film.The effects of polyphenols on the physicochemical properties and in vitro digestibility of Tartary buckwheat starch (TBS) remain scarce. In this study, the rheological, thermal properties, and in vitro digestibility of pregelatinized TBS (pre-TBS) with quercetin complexation at various concentrations were characterized. It was found that quercetin complexation increased the sh

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