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https://www.selleckchem.com/products/sodium-succinate.html 24; 95% CI 0.04-0.44; P = .018) and lower perceived well-being (3.4 point lower score on the Outcome Rating Scale; 95% CI -5.7 to -1.2; P = .003). Well-being was negatively associated with being in the app group, being older, and having higher levels of mental distress, and was positively associated with the perceived ability to make changes ('self-efficacy of quitting'). Conclusion The higher proportion of women in the app group indicated that the app did capture an expanded segment of the cannabis-using population. The app can be an alternative for those who are not yet prepared to seek treatment in formal healthcare services. The high level of depressive symptoms and lower levels of well-being among the app respondents suggest that some app users might need additional support. © The Author(s) 2020.Aim This study aimed to analyze the primary stability of dental implant in maxillary and mandibular anterior and posterior regions using a finite element analysis. Materials and methods CBCT images of maxillary and mandibular regions were collected from patients' radiographic data and transformed to 3D models. A Straumann Dental implant was inserted in each bone model and then pulled-out, where amount von-Mises stress was obtained and analyzed for each. A comparison between the insertion and the pull-out was evaluated. Results Twenty-four images were randomly selected for analysis from 122 scans. In both the insertion and the pull-out of the dental implant, von-Mises stress was high in cortical as compared to the cancellous bone (p  less then  0.0001). Maxillary posterior region had a low von-Mises stress (p  less then  0.001). Bone plastic deformation was higher in cancellous than the cortical bone in all bone regions and was the lowest in maxillary posterior region (p  less then  0.001). Bone displacement decreased from Type I to type IV bone. Conclusion Evaluation of von-Mises stress showed different measurem

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