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https://www.selleckchem.com/products/SB-202190.html WCO-based heating technology has the same effect on the reduction of GWC100 value as other modern energy carriers while also being cheaper and sustainable, long term. Reducing household emissions by substituting raw coal with green energy is a vital strategy to support pathways for sustainable environment design. The results of this work for the coal-to-WCO shift can reinforce the support for coal phase-out in China. Although the genetic and hormonal risk factors of breast cancer are well identified, they cannot fully explain the occurrence of all cases. Epidemiological and experimental studies have suggested that exposure to environmental pollutants, especially those with potential estrogenic properties, as polychlorinated biphenyls (PCBs) may have a role in breast cancer development. Being the most abundantly detected in human tissues and in the environment, congener 153 (PCB153) is widely used in epidemiological studies as indicator for total PCBs exposure. We aimed to estimate the association between cumulative atmospheric exposure to PCB153 and breast cancer risk. We conducted a case-control study of 5222 cases and 5222 matched controls nested within the French E3N cohort from 1990 to 2011. Annual atmospheric PCB153 concentrations were simulated with the deterministic chemistry-transport model (CHIMERE) and were assigned to women using their geocoded residential history. Their cumulative PCB153 exposure was calbreast cancer risk, which may be limited to ER-positive breast cancer. These results warrant confirmation in further independent studies but raise the possibility that exposure to PCB153 increase breast cancer risk. This study is the first to have estimated the impact of atmospheric exposure to PCB153 on breast cancer risk. Our results showed a statistically significant increase in breast cancer risk, which may be limited to ER-positive breast cancer. These results warrant confirmation in further indepen

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