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https://www.selleckchem.com/products/cx-5461.html To determine the structure and mechanisms of interaction of asthenic disorders with negative and positive psychopathological symptoms in hypochondriac schizophrenia. The study included male and female patients, aged 17-69 years, with a diagnosis of hypochondriac schizophrenia (F20.80 according to ICD-10) and asthenia symptoms. The main research method was clinical, which was supplemented by pathopsychological examination and the use of psychometric scales (PANSS, SANS, MFI-20,VAS asthenia). Asthenia in case of hypochondriac schizophrenia (schizoasthenia) integrates two unrelated phenomena «weakness» and «exhaustion» (intolerance to stress), and also acts within the framework of three psychopathological syndromes neurotic, senestopathic/hypochondriac and overvalued hypochondria. Asthenia with hypochondriac schizophrenia is a predictor of an unfavorable social and clinical prognosis. Integrating into the structure of the clinical manifestations of hypochondriac schizophrenia, asthenia forms close relationhrenia. The purpose of this study was to assess the relationship between power output and relative power output at the functional threshold power, ventilatory threshold and respiratory compensation point in road cyclists. Forty-six road cyclists (age 38 ± 9 years; height 177 ± 9 cm; body mass 71.4 ± 8.6 kg; body mass index 22.7 ± 2.2 kg·m-1; fat mass 7.8 ± 4%, VO2max 61.1 ± 9.1 ml·min-1·kg-1) performed a graded exercise test in which power output and relative power output at the ventilatory landmarks were identified. Functional threshold power was established as 95% of the power output during a 20-minute test. Power output and relative power output at the functional threshold power were higher than at the ventilatory threshold (p < 0.001). There were very large to near perfect correlations for power output (95% CI for r from 0.71 to 0.9) and relative power output (95% CI for r from 0.79 to 0.93) at the functional thres

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