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https://www.selleckchem.com/products/su5402.html Type 2 diabetes (T2DM) and Parkinson's disease (PD) are prevalent diseases that affect an aging population. Previous systematic reviews and meta-analyses have explored the relationship between diabetes and the risk of PD, but the results have been conflicting. The objective was to investigate T2DM as a determinant of PD through a meta-analysis of observational and genetic summary data. A systematic review and meta-analysis of observational studies was undertaken by searching 6 databases. We selected the highest-quality studies investigating the association of T2DM with PD risk and progression. We then used Mendelian randomization (MR) to investigate the causal effects of genetic liability toward T2DM on PD risk and progression, using summary data derived from genome-wide association studies. In the observational part of the study, pooled effect estimates showed that T2DM was associated with an increased risk of PD (odds ratio [OR] 1.21, 95% confidence interval [CI] 1.07-1.36), and there was some eviders. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. Cardiac hibernoma is a very rare benign cardiac tumour. We report a case of its surgical management. A case study with retrospective review of prospective patient data. A 60 year old male who presented with acute shortness of breath was found to have SVC compression on cardiac imaging. At operation the tumour was in the right atrial wall invading the intra-atrial groove and extending over superior vena cava (SVC), causing significant symptoms of SVC obstruction and tamponade. This was resected and the right atrium was reconstructed with Bovine pericardial patch. He was discharged home well. Cardiac hibernoma is a rare tumour which can be successfully treated by surgical excision. Cardiac hibernoma is a rare tumour which can be successfully treated by surgical excision. Contemporary eye care increas

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