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https://www.selleckchem.com/products/retatrutide.html Purpose We conducted a feasibility 2×2 factorial trial comparing N-methyl-D-aspartate (NMDA) antagonists (intravenous ketamine and oral memantine) versus placebo and intravenous steroids versus placebo, in patients having elective video-assisted thoracic surgery lobectomies, at St. Joseph's Hamilton, Canada, and Cleveland Clinic, Cleveland, USA. Our feasibility objectives were 1) recruitment rate/week; 2) recruitment of ≥90% of eligible patients; and 3) >90% follow-up. Secondary objectives were incidence and intensity of persistent post-surgical pain (PPSP) and other clinical and safety outcomes. Methods Using computerized randomization, patients were allocated to one of four groups NMDA active with steroid placebo; NMDA placebo with steroid active; both NMDA and steroid active; both NMDA and steroid placebo. Patients, health providers, and data analysts were blinded to allocation. Patients were followed for 3 months after randomization. Results The trial was initiated in May 2017 at Hamilton and, after subseegistration NCT02950233. © 2020 Shanthanna et al.Objective A bibliometric approach using quantitative analytical methods was applied to explore the development of research investigating acupuncture for the treatment of pain. This study also evaluated the current status of acupuncture analgesia with a visualization analysis of journal articles. Methods Articles on acupuncture for pain control that were published from 2000 to 2019 were retrieved from the Web of Science database. Extracted records were analyzed in terms of year of publication, country, journal, research area, authors, and organizational affiliations. The VOSviewer program was used to visualize trends in research on acupuncture for pain control. Results Analyses of 4595 original and review articles revealed that the total number of publications has continually increased over the last 20 years. The country producing the most articles in this field

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