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https://www.selleckchem.com/products/bgb-283-bgb283.html Gait asymmetry, one of the hallmarks of post stroke locomotion, often persists despite gait rehabilitation interventions, impacting negatively on functional mobility. Real-time feedback and biological cues have been studied extensively in recent years, but their applicability to post-stroke gait symmetry remain questionable. This proof-of-concept study examined the feasibility and instantaneous effects of real-time visual feedback provided in the form of an avatar in twelve participants with stroke on gait symmetry and other gait-related outcomes. The visual avatar was presented via three different views from the back, front and paretic side. Avatar feedback from the paretic side view showed significant increase in bilateral step length, paretic swing time ratio and treadmill walking speed, but no significant differences were found in symmetry measures in any of the three views. Those who had changes in symmetry ratio>0 were grouped as responders to spatial symmetry improvement in the side view. The responders had a significantly higher Chedoke-McMaster Stroke Assessment foot score and presented with a larger initial step length on the paretic side. Furthermore, all participants provided positive feedback and no adverse effects were observed during the experiment. Overall, these findings suggest that real-time avatarbased feedback can be used as an intervention to improve poststroke gait asymmetry.Spinal cord injury (SCI) is a widespread, life-altering injury leading to impairment of sensorimotor function that, while once thought to be permanent, is now being treated with the hope of one day being able to restore function. Surface electromyography (EMG) presents an opportunity to examine and promote human engagement at the neuromuscular level, enabling new protocols for intervention that could be combined with robotic rehabilitation, particularly when robot motion or force sensing may be unusable due to the us

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