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https://www.selleckchem.com/products/elenbecestat.html BACKGROUND Hypoxic hypoperfusion injury in the brain is a cause of potential injury and even death in the growth period of newborns. Therefore, monitoring regional cerebral oxygen saturation (CrSO₂) during this period is particularly important. This observational clinical study from a single center aimed to investigate the factors associated with CrSO₂ in full-term newborn infants during birth transition. MATERIAL AND METHODS We enrolled 84 full-term newborn infants delivered by cesarean section. We started the stopwatch with the obstetrician clamping the newborns' umbilical cords and recorded the values of newborns' CrSO₂, pulse oxygen saturation (SpO₂), pulse rate (PR), end-tidal carbon dioxide (EtCO₂), and respiratory rate (RR) at 2 min, 5 min, and 10 min. We weighed the newborns before they left the operating room and used statistical methods to compare the correlation between each observation factor. RESULTS Pearson correlation coefficients between CrSO₂ and SpO₂ measured at 2 min, 5 min, and 10 min were 0.491, 0.599, and 0.587, respectively (P0.05). CONCLUSIONS This study showed a correlation between CrSO₂ and SpO₂ and CrSO₂ and EtCO₂ during birth transition of full-term infants delivered by elective cesarean section, but CrSO₂ had no significant correlation with neonatal weight, PR, or RR.BACKGROUND Unruptured vertebral artery dissection (VAD) that causes ischemic infarction may require anticoagulant therapy or other treatments. However, anticoagulation therapy is not recommended for patients without ischemic infarction. To date, there has been no research on the imaging characteristics of patients with ischemic hypoperfusion that have a negative routine MRI scan. MATERIAL AND METHODS Patients with suspected VAD were recruited between June 2015 and June 2020 in order to perform high-resolution magnetic resonance imaging (HR-MRI). In total, 26 patients with negative MRI routine scans that underwent arteria

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