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https://www.selleckchem.com/products/pitstop-2.html Theoretical implications of the results regarding how reward influences attentional processing are discussed.The ability of two Panepinto micro pigs and two Yorkshire pigs (Sus scrofa) to acquire a joystick-operated video-game task was investigated. Subjects were trained to manipulate a joystick that controlled movement of a cursor displayed on a computer monitor. The pigs were required to move the cursor to make contact with three-, two-, or one-walled targets randomly allocated for position on the monitor, and a reward was provided if the cursor collided with a target. The video-task acquisition required conceptual understanding of the task, as well as skilled motor performance. Terminal performance revealed that all pigs were significantly above chance on first attempts to contact one-walled targets (p less then 0.05). These results indicate that despite dexterity and visual constraints, pigs have the capacity to acquire a joystick-operated video-game task. Limitations in the joystick methodology suggest that future studies of the cognitive capacities of pigs and other domestic species may benefit from the use of touchscreens or other advanced computer-interfaced technology.The ability to sequence thoughts and actions is impaired in Parkinson's disease (PD). In PD, a distinct error pattern has been found in the offline performance of sequential working memory. This study examined how PD's performance of sequential working memory unfolds over time using mouse tracking techniques. Non-demented patients with mild PD (N = 40) and healthy controls (N = 40) completed a computerized digit ordering task with a computer mouse. We measured response dynamics in terms of the initiation time, ordering time, movement time, and area under the movement trajectory curve. This approach allowed us to distinguish between the cognitive processes related to sequence processing before the actual movement (initiation time and ordering

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