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https://www.selleckchem.com/products/epacadostat-incb024360.html For simulated signals, it is found that synchrosqueezing with short-time Fourier transform has a better effect on extracting the characteristic frequencies. For the EEG signal, it is found that the method combining synchrosqueezing with short-time Fourier transform and coherent demodulation has a higher accuracy and information translate rate than other methods. The method combining synchrosqueezing with short-time Fourier transform and coherent demodulation proposed in this paper can be applied in the SSVEP system based on trinary frequency shift keying modulated stimuli. The method combining synchrosqueezing with short-time Fourier transform and coherent demodulation proposed in this paper can be applied in the SSVEP system based on trinary frequency shift keying modulated stimuli. In neonatal mice, sevoflurane, inspired through the nasal cavity to act as anesthesia, triggers neuronal apoptosis, inflammation and oxidative injury that can hamper cognitive functions in the growth of the central nervous system in the later stages of life. Our study aimed to explore the potential neuroprotective effects of protocatechuic acid (PCA) to ameliorate neonatal sevoflurane-induced neurotoxicity. Male mice were pretreated with PCA (10 or 20 mg/kg) for half an hour before continuous treatment for 6 h with 3 % sevoflurane. TUNEL staining was performed to examine the apoptotic cells to record their count. ELISA was performed to evaluate the expressions of the proteins - IL-1β, IL-18 and TNF-α. Analysis of the Western blot and test of the Morris maze was determined and the results analyzed. TUNEL findings assay showed a significant reduction with sevoflurane in neuronal apoptosis treated with PCA at 20 mg/kg. The expression of protein Caspase-3 showed significant changes in the group SEV + PCA ed neurobehavioral dysfunction. Parkinson's disease (PD) is a progressive neurodegenerative disorder that is related to neur

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