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https://www.selleckchem.com/products/acy-775.html 95 ([Formula see text]0.03).Conclusions This research shows that the diagnostic algorithm can be valuable for non-invasive diagnosis of cervical cancer. This is a significant step toward the development of a tool for tissue assessment of cervical cancer.AbstractsBackground Although molluscum contagiosum virus (MCV) infection is a common disease widespread among children and young adults, there is no shared opinion on treatment which can be divided into physical, chemical, medical( immunomodulating or anti-viral). According to some authors, MCV is best left to clear by itself.Objectives To assess the clearance of MCV lesions in a sample of paediatric patients. It compares outcomes in treated with Imiquimod cream, compared with non-treated patients.Methods The sample consits of 48 paediatric patients affected by MVC clinically diagnosed. It was divided into two groups Group I, treated with Imiquimod 5% cream once/day until the onset of a visible inflammatory reaction. Once the reaction was illicited, application was suspended until the irritation resolved. If the lesion was still present, drug was administered again using the same regimen. The cycle was repeated until complete clinical resolution.Group II, control, comprises non-treated patients. Follow up visits were carried out 12, 16, 20, 48 and 52 weeks from the beginning of treatment.Results At week 20 all patients except one in the treated group were lesion free. Persistence of MCV lesions was documented in one patient only until week 48. In the control group all patients were still affected by MCV lesions during the follow-up period. Spontaneous clinical resolution of the infection was observed in only 2 patients at week 52. The results of the study shows Imiquimod's significant efficacy.Conclusions Our study is one of the few case-control studies in paediatric population carried out with such long-term follow-up. Efficacy of this personalised treatment, scarce
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