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Fine particulate matter (PM2.5) is an important environmental factor affecting human health. However, most studies on PM2.5 and health have used data from fixed monitoring sites to assess PM2.5 exposure, which may have introduced misleading information on the exposure-response relationship. We aimed to assess the effect of short-term personal PM2.5 exposure on lung function in patients with chronic obstructive pulmonary disease (COPD) and asthma. To achieve this, we conducted a longitudinal panel study among 37 COPD patients and 45 asthma patients from Beijing, China. The COPD group and the asthma group completed 148 and 180 lung function tests, respectively. We found that in COPD patients, for every 10-μg/m3 increase in PM2.5 exposure at lag2, the FEV1, FVC and DLco decreased by -0.014 L (95% CI -0.025, -0.003), -0.025 L (95% CI -0.050, -0.003) and -0.089 mmol/min/kPa (95% CI -0.156, -0.023), respectively. There was also a decrease of -0.023 L/s (95% CI -0.042, -0.003) and -0.017 L/s (95% CI -0.032, -0.002) in MMEF at lag3 and lag03, respectively. In the asthma group, every 10-μg/m3 increase in PM2.5 exposure led to a reduction of -0.012 L (95% CI -0.023, -0.001), -0.042 L (95% CI -0.081, -0.003) and -0.061 L/s (95% CI -0.116, -0.004) in the FEV1, FVC and PEF at lag3, respectively. Our findings suggest that PM2.5 exposure may primarily affect both airway function and lung diffusion function in COPD patients, and airway function in asthma patients.The objective of this paper is to assess the sustainability of supply chains by proposing a dynamic network data envelopment analysis (DNDEA) model in the presence of interval data, due to the fact that in many real-world applications, the condition of convexity in the production technology might be violated. To prevent this issue, a DNDEA model based on the free disposal hull (FDH) approach is developed. For the first time, this paper develops a DNDEA version of the free disposal hull (FDH) model in the context of the SCOR framework. It is also shown that this model always presents a finite efficiency score for assessing the sustainability of supply chains. Moreover, using this model, real benchmarks can be calculated to improve the sustainability of unsustainable supply chains. https://www.selleckchem.com/products/mpi-0479605.html A case study in print industry is given. The results validate our proposed model.Recent advancements in environmental monitoring and analysis have created public and institutional awareness on the social and health impacts of air pollution at public places of tourists' attraction. Monuments stand as the celebrated remnants of bygone representations in the social and cultural tradition of any civilised state. India, being one of the oldest and live civilisations, owns numerous places of historical evidences in the form of both constructed museums and living monuments such as temples and palaces. Continuous exposure to the emission of gaseous and particulate pollutants has made remarkable evidences of damage to the artefacts and monumental structures located in major cities of the world. The aim of this study is to present an overview of the scientific attempts pertaining to the evaluation of impacts of air pollution and other meteorological changes on the historical monuments in India in the context of the global scenario. It is observed that seasonal fluctuations in the outdoor climate and increased human activities in the vicinity of the museums have plausible impacts on the immediate changes in the indoor air quality. The variations in the outdoor air quality are greatly affected by the traffic emissions and industrial emissions, while the indoor air quality is mostly affected by the improper ventilation and lack of proper control measures. The study provides strategies for developing air quality standards for museum environment and proposes a few technical and administrative solutions to improve the air quality for indoor museums as well as outdoor monuments.Natural ferrous minerals are readily available and recyclable catalysts in photo-Fenton-like oxidation for wastewater treatment. In this work, typical ferrous oxide and sulfide minerals including magnetite, chalcopyrite, and pyrrhotite were exploited as catalysts in heterogeneous photo-Fenton oxidation for purification of biological effluent of dyeing wastewater. In a wide initial pH range (3.0~7.5), ferrous mineral-based heterogeneous photo-Fenton-like reactions were proven to be effective on the oxidation of recalcitrant pollutants. COD removals achieved 60.57%, 58.83%, and 57.41% using pyrrhotite, chalcopyrite, and magnetite, respectively, as catalyst under ultraviolet irradiation of 220~275 nm at H2O2 concentration of 9.8 mM. The corresponding COD removals were 51.75% and 34.09% with or without ferrous sulfate additions in UV/H2O2 systems. Minerals exhibited excellent stability and reusability with photo-catalytic activity reduction of less than 10% in the reuse of 5 cycles. Dissolved iron concentrations were determined to be 1.86 mg L-1, 4.62 mg L-1, and 7.53 mg L-1 for magnetite, chalcopyrite, and pyrrhotite, respectively, at pH 3 and decreased to zero in neutral pH environment, which were much lower than those required for homogenous Fenton reaction. It was deduced that oxidation of recalcitrant pollutants was mainly catalyzed by Fe(II) on the mineral surface. The more reactive oxygen species such as hydroxyl radicals were resulted from the reaction of surface Fe (II) with H2O2, H2O2 photolysis, and charge separation of minerals under UV irradiation.Lung cancer is the most aggressive as well as deadly form of cancer and most of the lung cancer cases are involved in direct smoking or passive smoking. Oxidative stress and pulmonary inflammation regulated by some transcription factors like Nrf2, NF-κB etc. play important roles in lung cancer. Various combinations of therapies are currently attributed to lung cancer treatment. A plethora of evidence supports that the consumption of plant-derived foods can prevent chronic diseases like cancer. Leaves of olive (Olea europaea L.) are rich in phenolic compounds which are having antioxidant and anti-inflammatory property. Also, bromelain from pineapple juice and from pineapple stem is a potent anti-inflammatory agent. We took a pragmatic approach to prevent carcinogenesis by supplementing the combination of these two extracts. In this study, we have tried to evaluate the amelioration of various hallmarks associated with benzo(a)pyrene-induced lung carcinogenesis upon the combinatorial treatment of ethanolic olive leaf extract (EOLE) and bromelain.
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