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NHP 150110 had the highest IOP and ICP in all periods; however, it had the lowest TLPG in all periods due to its relatively thick LC. The other two NHPs showed similar shifts in the rank order of possible glaucoma risk factors. IOP is the only modifiable and readily measurable pressure-based risk factor for glaucoma. However, other potential risk factors such as ICP, TLP, and TLPG, as well as their rank-order patterns, differed compared to IOP across subjects, demonstrating that a comprehensive view of relevant risk factors is warranted. Future studies should consider including CSFP, TLP, and TLPG in addition to IOP as potential risk factors when assessing eye-specific glaucoma susceptibility. Future studies should consider including CSFP, TLP, and TLPG in addition to IOP as potential risk factors when assessing eye-specific glaucoma susceptibility. To evaluate the feasibility of using signal detection theory (SDT) in estimating criterion and detectability indices for corneal pneumatic stimuli and test corneal psychophysical data against linking hypotheses from nonprimate physiology using Bayesian analysis. Corneal pneumatic stimuli were delivered using the Waterloo Belmonte esthesiometer. Corneal thresholds were estimated in 30 asymptomatic participants and 1.5× threshold stimuli were used as signals (with 0.4 probability). There were 100-trial mechanical and cold stimulus experiments and 50-trial chemical experiments. Trials were demarcated auditorily and "yes" or "no" recorded after each trial. Cold stimulus experiments were conducted with 0.6 signal probability. Criterion ( ), likelihood ratio (lnβ), and ' were calculated from the yes-no responses. Average ' was 0.59 ± 0.1, 1.65 ± 0.37, and 1.14 ± 0.3 units for cold, mechanical, and chemical stimuli, respectively. Bayes factors obtained using Bayesian analysis of variance mildly favored (BF = 1.55) differences between 's of the stimulus types, with no support for differences in criteria between stimulus types. Multiple comparisons of ' supported linking hypotheses based on nociception and nerve conductance theories. Our experiments are the first to demonstrate the feasibility of estimating SDT indices and test different hypotheses. The conservative strategy (reporting "no" more often) chosen by participants was anticipated due to relatively large proportion of catch trials. SDT when using pneumatic esthesiometry is vital to evaluate bias in responses of participants. Considering the varied forms of inherent noise in the corneal sensory system, SDT is critical to understand the sensory and decisional characteristics. SDT when using pneumatic esthesiometry is vital to evaluate bias in responses of participants. Considering the varied forms of inherent noise in the corneal sensory system, SDT is critical to understand the sensory and decisional characteristics. To show the importance of measuring the angular distribution of straylight as an in vitro test for intraocular lenses (IOLs). The optical integration method was implemented to measure the point spread function, up to 5.1°, of IOLs immersed in a wet cell. The straylight parameter was calculated as the product of the point spread function by the squared angle. The effect of the scattered light is shown in extended images of a target surrounded by headlamps as glare sources. Three different IOLs were tested (1) AcrySof IQ SN60WF, monofocal, (2) AcrySof IQ PanOptix, trifocal, and (3) Tecnis Symfony ZRX00, bifocal with extended depth of focus. Measurements were compared to previously reported clinical studies where the same IOL models were implanted. The mean amount of scattered light, between 1.0° and 5.1°, generated by each IOLs were, in deg sr units (1) 1.2, (2) 12.1, and (3) 33.4. Lens (3) present a high amount of straylight related to a halo of an approximate diameter of 2°. In vitro measurements of the angular distribution of the point spread function of different types of IOLs showed important aspects related to their manufacturing quality. These results are in line with previous clinical findings where glare sensitivity was tested in the same angular range. In vitro measurement of angular dependence of straylight in IOLs, regardless their design, provides a valuable feedback to improve their optical quality. The minimization of the amounts of straylight positively impacts the recurrence of photic phenomena. In vitro measurement of angular dependence of straylight in IOLs, regardless their design, provides a valuable feedback to improve their optical quality. The minimization of the amounts of straylight positively impacts the recurrence of photic phenomena.[This corrects the article DOI 10.1167/tvst.9.2.12.].[This corrects the article DOI 10.1167/tvst.9.10.18.]. To compare the chromatic performance of the Bausch & Lomb Versario 3F trifocal intraocular lens (IOL) with the PhysIOL FineVision MicroF trifocal IOL and the Johnson & Johnson Vision TECNIS Symfony ZXR00 extended range of vision (ERV) IOL. The through-focus energy efficiency (TF-EE) was measured in vitro with red (R), green (G), and blue (B) wavelengths and was used to obtain the focus powers and longitudinal chromatic aberrations (LCAs) for each IOL. Other metrics, derived from the RGB TF-EE curves, were assessed for a more complete description of the chromatic performance of the IOLs. Both of the trifocal IOLs, although not specifically designed to tackle chromatic aberrations, showed acceptable LCA (≤0.50 D) in all foci with more balanced R and B efficiencies of their foci. Despite having the lowest TF-EE value at all foci, the Versario 3F demonstrated the most balanced chromatic performance with the smoothest energy transition among all foci and the smallest chromatic span. https://www.selleckchem.com/products/diphenhydramine.html The Symfony lens energy efficiency and longitudinal chromatic aberration) provides objective and complementary information that helps to interpret the visual quality outcomes of pseudophakic patients obtained in clinics. Acuity tests for infants and young children use preferential looking methods that require a perceptual match of brightness and color between grey background and target spatial average. As a first step in exploring this matching, this article measures photometric and colorimetric matches in these acuity tests. The luminance, uniformity, contrast, and color spectra of Teller Acuity Cards, Keeler Acuity Cards for Infants, and Lea Paddles under ambient, warm, and cold lighting, and of grey-emulating patterns on four digital displays, were measured. Five normal adults' acuities were tested at 10 m observationally. Luminance and spectral mismatches between target and background were found for the printed tests (Weber contrasts of 0.3% [Teller Acuity Cards], -1.7% [Keeler Acuity Cards for Infants], and -26% [Lea Paddles]). Lighting condition had little effect on contrast, and all printed tests and digital displays met established adult test luminance and uniformity standards. Digital display grey backgrounds had very similar luminance and color whether generated by a checkerboard, vertical grating, or horizontal grating.
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