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https://www.selleckchem.com/products/cp21r7-cp21.html 79% and included respiratory symptoms (49.14%), vomiting (38.79%), retinopathy of prematurity (ROP, 25.86%), hypoxic-ischemic injury (3.45%), re-hospitalization (26.72%) and sudden death (0.86%). Respiratory diseases constituted the most frequent complication. The prevalence of GER in BPD was 42.24% and included acid GER (18.10%) and duodenogastroesophageal reflux (DGER, 24.14%). Risk factors for respiratory symptoms were gestational age ≤30 weeks (odds ratio, OR=3.213; 95% CI, 1.221-8.460), birth weight 7 days (OR=4.952; 95% CI, 1.508-16.267), acid GER (OR=4.630; 95% CI, 1.305-16.420), and DGER (OR=5.588; 95% CI, 1.770-17.648). Infants with BPD and DGER were more prone to late complications than those with acid GER or no-reflux. Interpretation The prevalence of late complications is high in infants with BPD. GER, and in particular, DGER, poses a tentative risk for these late complications.Background Obstructive sleep apnea (OSA), a common co-morbidity in ILD, could contribute to a worsened course if untreated. It is unclear if adherence to CPAP therapy improves outcomes. Methods We conducted a ten-year retrospective observational multicenter cohort study, assessing adult patients with ILD who had undergone polysomnography. Subjects were categorized based on OSA severity into 'no/mild OSA' (AHI less then 15) or 'moderate/severe OSA' (AHI ≥15). All subjects prescribed and adherent to CPAP were deemed to have 'treated OSA'. Cox regression models were used to examine the association of OSA severity and CPAP adherence with all-cause mortality risk and progression-free survival (PFS). Results Of 160 subjects that met inclusion criteria, 131 had OSA and were prescribed CPAP. 66 patients (41%) had no/mild untreated OSA, 51 (32%) had moderate/severe untreated OSA, and 43 (27%) had treated OSA. Subjects with no/mild untreated OSA did not differ from those with moderate/severe untreated OSA in mean survival time (127±56 mo

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