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The mean ages were 44.52 (±16.61) and 45.49 (±15.84) years, with 70.3% males and approximately half Malay ethnics. https://www.selleckchem.com/products/Eloxatin.html The changes of knowledge and comparison of Topical Application Assessment Score between the groups showed an incremental raise of significance with every visit ( = 0.006 [week 1], 0.004 [week 6], and 0.002 [week 12]). Psoriasis Area and Severity Index 75 could not draw any conclusion as patients who achieved >75% improvement were inadequate. C and P labeling was effective in improving the understanding and knowledge of patients with psoriasis. Both groups showed improvement in body surface area and Dermatology Life Quality Index for every visit; however, it was statistically insignificant. C and P labeling was effective in improving the understanding and knowledge of patients with psoriasis. Both groups showed improvement in body surface area and Dermatology Life Quality Index for every visit; however, it was statistically insignificant. This study aimed to evaluate the phytochemicals screening of (Roxb) bark and to analyze the enzymatic activities of its various organic fractions. Crude methanolic fraction of (Roxb) bark and its respective fractions were screened for the presence of different phytochemicals with different reagents. On the basis of increasing order of polarity, different organic solvents were used to obtain different fractions. Enzymatic studies were performed on crude methanolic extract of the plant. All the assays were performed under standard conditions. The phytochemical analysis shows the presence of alkaloids, phenols, triterpenoids, phytosterols, and flavonoids. Phenolic compounds and flavonoids are the major constituents of the plant. In anticholinesterase assay, the percent inhibition of standard drug (eserine) was 91.27 ± 1.17 and the half maximal inhibitory concentration (IC ) was 0.04 ± 0.0001. For α-glucosidase inhibition, the IC value for Dichloromethane fraction was 8.45 ± 0.13, for Methanol fcer, asthma, and Alzheimer. Furthermore, the extracts of this plant can be used in their crude form, which is an addition to the complementary and alternative treatment strategies. has antioxidant and free-radical-scavenging properties. Malathion is the most common organophosphate, which is capable to produce free radicals and induce disturbance on some of male reproductive parameters. This study was designed to evaluate the effects of extract against damage induced by Malathion to the reproductive parameter of male rats. In this experimental study, 48 male Wistar rats were randomly assigned to eight groups first group, sham group (normal saline); second group, Malathion (250 mg/kg) group; third to fifth groups, groups (2.5, 5, and 10 mg/kg body weight, respectively); and sixth to eight groups, Malathion + groups (2.5, 5, and 10 mg/kg). extract (2.5, 5, and 10 mg/kg body weight, respectively) administrated orally, and daily for 8 weeks. The sperm parameters, testis malondialdehyde (MDA), serum total antioxidant capacity, serum testosterone level, and the height of germinal layer were evaluated and analyzed statistically. All the values of male reproductive parameters reduced significantly in the Malathion group as compared to the sham group ( < 0.01) except MDA level, which increased significantly. The and Malathion treatments in all doses increased the whole parameters significantly as compared to the Malathion group ( < 0.01) except MDA level, which decreased significantly. No significant changes were observed in all groups as compared to the sham group ( > 0.05). extract administration attenuates the toxic effects of Malathion on some of the male reproductive parameters. Tribulus terrestris extract administration attenuates the toxic effects of Malathion on some of the male reproductive parameters. Patients and their healthcare providers' are in need to access a correct and complete list of all patients' active bills for safe and effective clinical care. Currently, Healthcare Information Systems are not providing a proper access to the patients' medications lists. Thus, this study aimed to evaluate the impact of community pharmacist-led medication reconciliation process in community pharmacies in the UAE through applying a pharmacist-patient-centered medication reconciliation (PPCMR). This was an interventional study of medication reconciliation process in 25 pharmacies in the UAE during July 1, 2019 till September 1, 2019. The participant pharmacists were surveyed and interviewed to gather more information about the barriers and enablers of the process before and after the implementation of PPCMR. After the implementation of PPCMR, medication reconciliation service was available in 84% of the pharmacies compared to 40% before the PPCMR ( = -2.84, = 0.005). The main workforce barriers to implropriateness of medication management and use. Diabetes mellitus is a chronic metabolic disease, which possibly leads to kidney, brain, heart failure, and other organ complications, subsequently harming human health. These symptoms have been prevented using the leaf of black mulberry (BM), as a traditional medicine, because the phenolic compounds contained are able to decrease blood glucose concentration. Meanwhile, previous reports have shown that BM contains 1-deoxynojirimycin, with strong activity as an α-glucosidase inhibitor. The aim of this study, therefore, was to formulate and evaluate BM leaf extract in lozenge dosage form as an α-glucosidase inhibitor. The leaves of BM were extracted using the maceration method, where ethanol (70%) served as a solvent, and the inhibitory activity of the sourced α-glucosidase enzyme was determined through study. Subsequently, the extract was formulated into lozenge dosage form and evaluated for physical stability and also the effect of α-glucosidase enzyme. The result showed an inhibitory activity of BM leaf extract against the enzyme α-glucosidase, with a half maximal inhibitory concentration (IC ) value of 357.6 μg/mL, whereas the lozenge formulation containing 43% of extract as well as 5% polyvinylpyrrolidone showed the best physical stability as compared to other formulas. However, the lozenge inhibits α-glucosidase enzyme with an IC value of 549.7 μg/mL. It was established that the lozenge of BM leaf extract possesses activity as an α-glucosidase inhibitor. It was established that the lozenge of BM leaf extract possesses activity as an α-glucosidase inhibitor.
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