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https://www.selleckchem.com/products/z-ietd-fmk.html A purified inulin-type fructan named ACNP (Asparagus cochinchinensis neutral polysaccharide) with apparent molecular weight of 2690 Da was obtained from Asparagus cochinchinensis (Lour.) Merr. by ion-exchange and gel-filtration column chromatography. Structural analyses reveal that ACNP has a linear backbone composed of 2,1-β-D-Fruf residues, ending with a (1→2) bonded α-D-Glcp. The impacts of ACNP on gut microbiota were then investigated by in vitro fermentation with human fecal cultures. The results showed that ACNP was digested by gut microbiota, while the pH value in the fecal culture of ACNP was greatly decreased, and total short-chain fatty acids, acetic, propionic, i-valeric and n-valeric acids were significantly increased. Moreover, ACNP regulated the fecal microbiota composition by stimulating the growth of Prevotella, Megamonas, and Bifidobacterium while depleting Haemophilus. Collectively, these results indicated that ACNP beneficially regulates gut microbiota, which thus suggested that ACNP has the potential to be used as a dietary supplement or drug to improve health.Ultrasound technique was successfully used to obtain nanostructured particles from native and esterified starch, able to support the antimicrobial potassium sorbate (PS). The starch used (native, acetate or oleate) affected the nanoparticles morphology and size globular or plate like shapes were observed for esterified and native starch respectively, while the hydrodynamic diameters were between 28 and 236 nm, with a trend towards smaller sizes for modified starches. The PS retention capacity ranged from 41.5 -90 mg/g, showing acetylated particles the highest value. The particles were amorphous and had a low average molecular weight of 1.9-6.7 × 105 Da. Water retention capacity and solubility (S) were higher for modified starch particles. PS addition had minor effect, increasing S and reducing the apparent amylose content, with respect to

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