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https://www.selleckchem.com/ ychometric scores.Cristobalite with ordered interstitial dual-sized mesopores was synthesized through the crystallization of silica colloidal crystals composed of monodispersed amorphous silica nanoparticles. An aqueous solution containing both a flux (Na2 O) and a carbon precursor (an aqueous low-molecular weight phenolic resin) was infiltrated into the interstices of silica colloidal crystals. The organic fraction in the nanocomposite was further polymerized and subsequently carbonized in an Ar flow at 750 °C to reinforce the colloidal crystal structure. The thermal treatment resulted in the crystallization of the colloidal crystals into cristobalite while retaining the porous structure. The cristobalite-carbon nanocomposite was calcined in air to remove the carbon and create interstitial ordered mesopores in the cristobalite. The surfaces of crystalline mesoporous silica are quite different from those of various ordered mesoporous silica with amorphous frameworks; thus, the present findings will be useful for a precise understanding and control of the interfaces between the mesopores and silica networks.Several patients with beta-propeller protein-associated neurodegeneration (BPAN)/static encephalopathy with neurodegeneration in adulthood have been reported to present Rett syndrome (RTT)-like features. This report presents an individual with BPAN showing clinical features of RTT. Psychomotor delay and epilepsy onset were noted at 1 year, and regression began at 4 years. Screening of the methyl-CpG binding protein 2 (MECP2) did not show variants. At 22 years, basal ganglia iron deposits were found on magnetic resonance imaging (MRI), and the WD-domain repeat 45 gene (WDR45) variant was identified. Review of the literature showed that BPAN with RTT-like features is associated with more epileptic seizures and less deceleration of head growth, breathing irregularities, and cold extremities than classic RTT with MECP2 variants. These clin
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