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https://www.selleckchem.com/screening/inhibitor-library.html Although, cannabis users call these substances "cannabis", synthetic cannabinoids have different pharmacological properties, which make them dangerous substances leading to more serious complications. Physicians dealing with cannabis users should be aware of these differences between vegetal cannabis and synthetic cannabinoids.Novel insight into suicidal behavior. This article presents four short examples of new insights into suicidal acts and innovative treatments. These include the results of cognitive neuroscience studies that have identified hypersensitivity to rejection, exclusion, and injustice signals in suicide attempters, as well as persisting trend for risky choices and insufficient cognitive control. These processes may be future therapeutic targets. Moreover, several studies showed on early suicidal trajectories, as well as residual epigenetic scars, as a result of childhood abuse. The people who were victims of these events may require specific intervention. In addition, artificial intelligence is a source of hope to account for the etiological and phenotypic complexity of suicidal behavior, and to establish more precise algorithms of medical decision-making. Ethical issues are raised at the same time. Finally, ketamine is today an innovative treatment (pending authorization) for the rapid reduction of suicidal ideation and a more effective crisis management.Collective measures to prevent suicide. Suicide is a preventable death that requires the implementation of individual and collective preventive actions. A simple and effective action is to limit the access to lethal means. School-based outreach programs reduce suicide attempts. The detection and management of depression by general practitioners plays an important role in suicide prevention. Furthermore, maintaining contact with people at high suicidal risk is a very promising method to prevent suicide.Suicide prevention after a suicide att

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