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https://www.selleckchem.com/products/ly2835219.html Objectives To review the scientific literature of studies on dental age estimation methods applied to Brazilian children. Methods A systematic literature review was designed according to thePRISMA guidelines and registered in PROSPERO (CRD42020136170).Six scientific databases were used as primary search sources(PubMed, Scopus, LILACS, SciELO, Embase and Web of Science) and two databases (Open Grey and Open Thesis) were searchedto partially select the "grey literature". Only cross-sectional studies were included. The risk of bias was assessed by means of Joanna Briggs Institute Critical Appraisal Tools for Systematic Reviews. The standardized mean difference (SMD) between the estimated dental and chronological ages was meta-analyzed viaa random effects model. Results The search resulted in2,527 studies, from which 13 met the eligibility criteria. Out of the eligible studies, 76.92% had low risk of bias and high methodological quality. Ten studies provided proper information to be included in the meta-analysis.Themethods and their SMD between estimated and chronological ages were Willems'=0.05, Lilequist and Lundberg's = -0.11, Nolla's = 0.22, Mornstad's = 0.27, Cameriere's = -0.31, Demirjian's = 0.74 and Haavikko's = -0.87. Conclusion Although originally trained in populations worldwide, most of the international methods for radiographic dental age estimation had optimal performance in Brazilian children.Switching from calcineurin-inhibitors (CNI) to everolimus >6-12-months after liver transplantation (LT) seems inefficient in improving renal function, but whether everolimus halts further renal-function decline compared to low-dose CNI remains unclear. In a retrospective single-center study of everolimus after LT (2008-2016) with routine measured glomerular filtration rates (mGFR; 51Cr-EDTA- or iohexol clearance), we compared by propensity-score matching everolimus therapy to low-dose CNI therapy. The study comprise

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