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https://www.selleckchem.com/products/z-vad(oh)-fmk.html Adenosine monophosphate (AMP)‑activated protein kinase (AMPK) is a major cellular energy sensor that is activated by an increase in the AMP/adenosine triphosphate (ATP) ratio. This causes the initiation of adaptive cellular programs, leading to the inhibition of anabolic pathways and increasing ATP synthesis. AMPK indirectly inhibits mammalian target of rapamycin (mTOR) complex 1 (mTORC1), a serine/threonine kinase and central regulator of cell growth and metabolism, which integrates various growth inhibitory signals, such as the depletion of glucose, amino acids, ATP and oxygen. While neuroprotective approaches by definition focus on neurons, that are more sensitive under cell stress conditions, astrocytes play an important role in the cerebral energy homeostasis during ischemia. Therefore, the protection of astrocytic cells or other glial cells may contribute to the preservation of neuronal integrity and function. In the present study, it was thus hypothesized that a preventive induction of energy deprivatins.Following the publication of this paper, the authors have realized that the first two authors on the paper, Jing Wang and Ruiting Li, should have been credited with joint first author status. Furthermore, the second author affiliation was presented incorrectly in the paper, and the corrected address, as this should have been featured, is included below. Therefore, the authors' affiliations and the affiliation addresses should have appeared as follows Jing Wang1*, Ruiting Li2*, Zhiyong Peng1, Bo Hu1, Xin Rao1 and Jianguo Li1. 1Department of Intensive Care Unit, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071; 2Department of Critical Care Unit, Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China. *Contributed equally. The authors confirm that there are no further errors in the s

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